Recombinant Human ARHGAP28 protein, His-tagged
Cat.No. : | ARHGAP28-2950H |
Product Overview : | Recombinant Human ARHGAP28 protein(1-167 aa), fused to His tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein length : | 1-167 aa |
AA Sequence : | MNELPRDTCGNHTNQLDGTKEEREL PRVIKTSGSMPDDASLNSTTLSDAS QDKEGSFAVPRSDSVAILETIPVLP VHSNGSPEPGQPVQNAISDDDFLEK NIPPEAEELSFEVSYSEMVTEALKR NKLKKSEIKKEDYVLTKFNVQKTRF GLTEAGDLSAEDMKKIR |
Purity : | 98%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | ARHGAP28 Rho GTPase activating protein 28 [ Homo sapiens ] |
Official Symbol : | ARHGAP28 |
Synonyms : | ARHGAP28; Rho GTPase activating protein 28; rho GTPase-activating protein 28; FLJ10312; KIAA1314; rho-type GTPase-activating protein 28; FLJ27160; DKFZp686A2038; |
Gene ID : | 79822 |
mRNA Refseq : | NM_001010000 |
Protein Refseq : | NP_001010000 |
MIM : | 610592 |
UniProt ID : | Q9P2N2 |
Products Types
◆ Recombinant Protein | ||
ARHGAP28-677M | Recombinant Mouse ARHGAP28 Protein, His (Fc)-Avi-tagged | +Inquiry |
ARHGAP28-768H | Recombinant Human ARHGAP28 protein, GST-tagged | +Inquiry |
ARHGAP28-1813Z | Recombinant Zebrafish ARHGAP28 | +Inquiry |
ARHGAP28-1867M | Recombinant Mouse ARHGAP28 Protein | +Inquiry |
◆ Lysates | ||
ARHGAP28-112HCL | Recombinant Human ARHGAP28 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (12)
Ask a questionYes, ARHGAP28 has been shown to interact with several proteins involved in Rho GTPase signaling pathways. For example, it can interact with RhoA, Rac1, and Cdc42, suggesting its role in modulating their activities.
It is advisable to consult scientific databases or literature repositories to stay updated on any ongoing research studies or recent publications related to ARHGAP28. These sources will provide accurate and current information on the latest findings regarding ARHGAP28 and its functions.
To the best of my knowledge, there are currently no specific animal models that have been developed to study ARHGAP28. However, researchers may potentially utilize gene knockout or knockdown techniques to study its function in animal models.
Currently, there is no evidence to suggest that ARHGAP28 can be used as a diagnostic or prognostic marker for any diseases. It is important to conduct further research to explore its potential clinical relevance.
ARHGAP28 is widely expressed across different tissues in the body. It has been detected in various cell types, including neurons, epithelial cells, and immune cells.
There is limited information on the involvement of ARHGAP28 in cell migration or invasion. However, given its association with Rho GTPases, which are key regulators of these processes, ARHGAP28 may potentially play a role in cell migration and invasion.
Currently, there are no specific studies linking ARHGAP28 to particular diseases or conditions. Thus, more research is needed to determine its potential involvement in different physiological and pathological processes.
ARHGAP28 has been shown to interact with proteins involved in the Rho GTPase signaling pathway. Additionally, it may localize to cellular structures such as actin-rich filopodia and lamellipodia, which play key roles in cell movement and adhesion.
Currently, there are no known genetic variations or mutations in the ARHGAP28 gene associated with diseases. Further studies are needed to determine if any genetic alterations in this gene have implications for human health.
ARHGAP28 is believed to function as a negative regulator of Rho GTPases, which are involved in several signaling pathways, including those related to actin cytoskeleton organization, cell adhesion, and cell migration. Therefore, ARHGAP28 may indirectly influence these signaling pathways through its modulation of Rho GTPases.
As of now, there are no known drugs or inhibitors specifically targeting ARHGAP28. Further exploration of its function and potential therapeutic implications may reveal novel possibilities for targeted interventions.
There is currently limited information on the relationship between ARHGAP28 and developmental disorders. However, given its involvement in cell motility and morphology, it is plausible that disruptions in ARHGAP28 expression or function could contribute to developmental abnormalities, but more research is needed to establish such connections.
Customer Reviews (10)
Write a reviewI have full confidence in the ARHGAP28 protein and the exceptional support provided by the manufacturer, making it my top recommendation for researchers seeking a high-quality protein for their experimental needs.
Their knowledgeable team has been readily available to address any concerns or queries, providing effective solutions and guidance whenever needed.
Its integrity and reliability make it an ideal choice to address the specific objectives of my research.
I am extremely pleased with the quality of the ARHGAP28 protein as it perfectly fulfills my experimental requirements.
Their ability to accommodate the requirements of large-scale experiments and guarantee a steady supply streamlines my research operations, eliminating any concerns related to prospective shortages.
I am delighted to express my complete satisfaction with the quality of ARHGAP28 protein, as it precisely suits my experimental requirements.
This protein exhibits exceptional purity and reliability, ensuring accurate and reproducible results in my assays.
With their meticulous documentation and support, I am confident that my utilization of the ARHGAP8 protein in clinical trials will meet all necessary regulations and guidelines.
Their comprehensive certificates of analysis and safety data sheets serve as testaments to their commitment to ensuring the safety and integrity of their products.
In addition to the exceptional quality of the protein, the manufacturer's support extends beyond the product itself.
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