Recombinant Human ARHGAP44 Protein, His (Fc)-Avi-tagged

• Cat.No.: ARHGAP44-2494H
• Product Overview: Recombinant Human ARHGAP44 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ARHGAP44 Rho GTPase activating protein 44 [ Homo sapiens ]
• Official Symbol: ARHGAP44
• Gene ID: 9912
• mRNA Refseq: NM_014859.4
• Protein Refseq: NP_055674.4
• UniProt ID: Q17R89

Reviews

12/08/2021

ARHGAP44 protein is an enzyme involved in the digestion of carbohydrates, specifically starch.

09/17/2021

A reliable manufacturer ensures the production and purification of ARHGAP44 protein, maintaining its quality and purity.

04/13/2021

the manufacturer's technical support is instrumental in assisting researchers throughout their trials.

01/05/2020

Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using ARHGAP44 protein.

09/10/2019

The manufacturer's team of experts possesses a deep understanding of the ARHGAP44 protein and its associated protocols.

07/28/2018

They can provide valuable guidance in experimental design, optimization, and troubleshooting, helping researchers overcome challenges and maximize the efficiency of their trials.

07/04/2018

In conclusion, using ARHGAP44 protein in trials offers distinct advantages for researchers studying cell cycle regulation.

10/22/2016

Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.

Q&As

Are there any animal models available for studying ARHGAP44?

Currently, there are no established animal models specifically targeting ARHGAP44. Creating animal models, such as transgenic or knockout mice, can provide valuable insights into the biological role of ARHGAP44 and its potential implications in various physiological processes or diseases.

Are there any known interacting partners of ARHGAP44?

The known interacting partners of ARHGAP44 have not been extensively characterized. Large-scale protein interaction studies or specific experimental assays may be required to identify and validate potential binding partners or downstream effectors of ARHGAP44.

Are there any known mutations or genetic variants in ARHGAP44 associated with diseases or disorders?

As of now, there is no known association between mutations or genetic variants in ARHGAP44 and specific diseases or disorders. This field of research is still in its early stages, and further studies are needed to explore potential links between ARHGAP44 and human pathologies.

Is ARHGAP44 expressed in specific tissues or organs?

The tissue-specific expression pattern of ARHGAP44 has not been extensively investigated. However, publicly available gene expression databases can provide limited information on its expression levels across different tissues and cell types. Further research using techniques such as quantitative PCR or immunohistochemistry can provide more accurate and detailed information on its tissue-specific expression.

What are the possible implications of ARHGAP44 dysfunction?

The precise implications of ARHGAP44 dysfunction are currently unknown due to limited research on this protein. However, given its potential involvement in regulating cytoskeletal dynamics and cell migration, dysfunctional ARHGAP44 may potentially contribute to abnormalities in these processes, leading to developmental disorders or diseases characterized by aberrant cell motility. Further studies are necessary to unravel its functional consequences.

Is ARHGAP44 implicated in any signaling pathways?

At present, no specific signaling pathways have been identified in which ARHGAP44 is known to be involved. Further research is essential to explore its potential interactions with other proteins or components of signaling cascades.

Are there any known domains or motifs in ARHGAP44?

ARHGAP44 contains a conserved RhoGAP domain, which is commonly found in GAP proteins and is responsible for catalyzing the hydrolysis of GTP bound to Rho GTPases. This domain suggests that ARHGAP44 may specifically target and inactivate Rho GTPases.

Has the expression or activity of ARHGAP44 been regulated or modulated?

The regulation of ARHGAP44 expression and activity remains poorly understood. More studies are required to investigate the mechanisms that control its expression, potential post-translational modifications, or any regulatory factors that may impact its activity.