Recombinant Human ARL14EP Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ARL14EP-6339H |
Product Overview : | C11orf46 MS Standard C13 and N15-labeled recombinant protein (NP_689529) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The protein encoded by this gene is an effector protein. It interacts with ADP-ribosylation factor-like 14 [ARL14, also known as ADP-ribosylation factor 7 (ARF7)], beta-actin (ACTB) and actin-based motor protein myosin 1E (MYO1E). ARL14 is a small GTPase; it controls the export of major histocompatibility class II molecules by connecting to the actin network via this effector protein. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 29.3 kDa |
AA Sequence : | MMDPCSVGVQLRTTNECHKTYYTRH TGFKTLQELSSNDMLLLQLRTGMTL SGNNTICFHHVKIYIDRFEDLQKSC CDPFNIHKKLAKKNLHVIDLDDATF LSAKFGRQLVPGWKLCPKCTQIING SVDVDTEDRQKRKPESDGRTAKALR SLQFTNPGRQTEFAPETGKREKRRL TKNATAGSDRQVIPAKSKVYDSQGL LIFSGMDLCDCLDEDCLGCFYACPA CGSTKCGAECRCDRKWLYEQIEIEG GEIIHNKHAGTRTRPLEQKLISEED LAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ARL14EP ADP ribosylation factor like GTPase 14 effector protein [ Homo sapiens (human) ] |
Official Symbol : | ARL14EP |
Synonyms : | ARL14EP; ADP ribosylation factor like GTPase 14 effector protein; ARF7EP; C11orf46; dJ299F11.1; ARL14 effector protein; ADP-ribosylation factor-like 14 effector protein; ARF7 effector protein |
Gene ID : | 120534 |
mRNA Refseq : | NM_152316 |
Protein Refseq : | NP_689529 |
MIM : | 612295 |
UniProt ID : | Q8N8R7 |
Products Types
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe specific interacting partners or binding partners of the ARL14EP protein have not yet been identified. Further research is needed to investigate its interactions with other proteins, lipid membranes, or cellular organelles to better understand its molecular mechanisms.
The specific subcellular localization of the ARL14EP protein is not well-characterized. However, based on its involvement in membrane trafficking and vesicular transport, it is likely to be found associated with membranes or membrane-bound organelles within cells.
Given the limited understanding of the ARL14EP protein's function and its potential role in diseases, it is difficult to determine whether it can be targeted for therapeutic purposes at this time. Further research is necessary to explore its therapeutic potential or identify any specific disease contexts where targeting ARL14EP could be beneficial.
To the best of our knowledge, no knockout or knockdown studies specifically targeting the ARL14EP protein have been published. Such studies could provide valuable insights into its functional importance and potential effects on cellular processes.
The regulation of ARL14EP expression is not well-understood. However, gene expression profiling studies or functional experiments could provide insights into potential regulatory mechanisms affecting ARL14EP expression under specific conditions.
Currently, there is no information available regarding specific post-translational modifications of the ARL14EP protein. Probing the protein's modifications, such as phosphorylation or ubiquitination, could provide further insight into its regulatory mechanisms and functional roles.
As of now, the structure of the ARL14EP protein has not been determined experimentally. Structural information about the protein can provide valuable insights into its function and interactions with other cellular components.
There is limited information available regarding genetic variations in the ARL14EP gene and their specific associations with disorders or diseases. Further studies are needed to explore any potential links between ARL14EP gene variations and specific pathological conditions.
Currently, there are no known disease associations directly linked to the ARL14EP protein. However, its involvement in membrane trafficking and intracellular transport processes suggests that dysregulation of ARL14EP could potentially contribute to various cellular dysfunctions.
ARL14EP shows a degree of conservation across different species, suggesting its importance in cellular processes. Comparative studies in various organisms can provide valuable insights into its evolutionary significance and functional conservation.
Customer Reviews (10)
Write a reviewthe stability of the ARL14EP protein enables me to conduct experiments over an extended period, reducing the need for frequent restocking and promoting experimental consistency.
With the manufacturer's unwavering dedication to delivering quality products and unparalleled technical support, I am confident in their ability to help me overcome any challenges and propel my research forward.
The ARL14EP protein exhibits several valuable attributes that make it an excellent choice for my trials.
This level of support saves researchers time and resources, enabling them to focus on the scientific aspects of their work and accelerate the overall progress of their studies.
If researchers require specific variants or modifications of ARL14EP protein, the manufacturer can work with them to provide customized products tailored to their needs.
Manufacturers may offer the option for custom protein production.
the ARL14EP protein offers significant advantages in trials due to its high quality, purity, and stability.
Their expertise can help troubleshoot problems, suggest alternative approaches, or provide recommendations for optimizing experimental protocols.
The manufacturer's commitment to excellence is evident through their provision of excellent technical support, which can prove vital in troubleshooting any experimental challenges or addressing specific research questions related to the protein.
Its high quality and purity ensure accurate and reliable results.
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