Recombinant Human ARMC8 293 Cell Lysate

• Cat.No.: ARMC8-8698HCL

Specification

• Description: Antigen standard for armadillo repeat containing 8 (ARMC8), transcript variant 3 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: ARMC8 armadillo repeat containing 8 [ Homo sapiens ]
• Official Symbol: ARMC8
• Synonyms: ARMC8; armadillo repeat containing 8; armadillo repeat-containing protein 8; DKFZP434A043; HSPC056; S863-2; MGC4880; MGC10058
• Gene ID: 25852
• mRNA Refseq: NM_213654
• Protein Refseq: NP_998819
• UniProt ID: Q8IUR7
• Chromosome Location: 3q22
• Function: binding

Reviews

12/30/2020

Great performance in ELISA.

12/14/2019

This may include options like different formulations, protein modifications, or tagging techniques. Customization can enhance the versatility of the protein and optimize its utility in the intended research.

04/06/2019

Its high purity and integrity provide the necessary assurance for consistent and reliable results, enabling me to achieve precise and meaningful outcomes in my research.

03/03/2018

The Armc8 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

06/10/2017

A manufacturer can serve as a collaborative partner, engaging in discussions, and exchanging knowledge with researchers.

07/04/2016

Such support ensures researchers have access to reliable tools and expertise, facilitating their investigations into the functions, mechanisms, and disease relevance of Armc8 protein.

Q&As

Are there any known genetic disorders or conditions associated with mutations in the ARMC8 gene?

Yes, mutations in the ARMC8 gene have been linked to a condition called ciliary dyskinesia, which is characterized by respiratory tract infections and impaired movement of cilia.

Can mutations in the ARMC8 gene cause other health problems besides ciliary dyskinesia?

Currently, ciliary dyskinesia is the only known health condition associated with mutations in the ARMC8 gene. However, further research might uncover additional associations in the future.

Is the ARMC8 protein involved in any signaling pathways?

While the exact signaling pathways involving the ARMC8 protein are not fully understood, it is known to interact with other proteins involved in cell cycle regulation and microtubule organization.

Is the expression of ARMC8 protein tissue-specific?

The ARMC8 protein is expressed in multiple tissues and organs, but its levels might vary depending on the specific tissue and developmental stage.

Does the ARMC8 protein have any binding partners?

Yes, the ARMC8 protein has been shown to interact with other proteins such as dynein, which is involved in cellular transport, and beta-catenin, which is a key component of the Wnt signaling pathway.

Is there ongoing research on the ARMC8 protein?

Yes, scientists continue to investigate the role and function of the ARMC8 protein, especially in relation to ciliary dyskinesia and other cellular processes it is involved in.

Are there any known drugs or treatments targeting the ARMC8 protein?

As of now, there are no specific drugs or treatments targeting the ARMC8 protein. However, understanding its role in various cellular processes may lead to potential therapeutic interventions in the future.