Recombinant Human ARPP21, GST-tagged

• Cat.No.: ARPP21-9890H
• Product Overview: Recombinant Human ARPP21 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-89a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARPP21 cAMP-regulated phosphoprotein, 21kDa [ Homo sapiens ]
• Official Symbol: ARPP21
• Synonyms: ARPP21; cAMP-regulated phosphoprotein, 21kDa; cAMP-regulated phosphoprotein 21; ARPP 21; R3H domain containing 3; R3HDM3; TARPP; thymocyte cAMP-regulated phosphoprotein; cyclic AMP-regulated phosphoprotein, 21 kD; RCS; ARPP-21; FLJ32997
• Gene ID: 10777
• mRNA Refseq: NM_001025068
• Protein Refseq: NP_001020239
• MIM: 605488
• UniProt ID: Q9UBL0
• Chromosome Location: 3p24.3
• Function: calmodulin binding; molecular_function; nucleic acid binding

Reviews

03/27/2023

Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.

07/28/2017

The ARPP21 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.

06/24/2016

Whether measuring analyte concentrations, screening for specific interactions, or monitoring immune responses, this protein's exceptional performance in ELISA experiments is truly commendable.

Q&As

Are there any drugs or compounds known to modulate ARPP21 activity?

Currently, there are no specific drugs or compounds known to directly modulate ARPP21 activity. Future research may identify potential compounds that could target ARPP21 for therapeutic purposes.

Is ARPP21 expressed in specific cell types or throughout the body?

ARPP21 is expressed in various cell types, including neurons in the brain. However, its expression pattern in different tissues and organs throughout the body is not well characterized.

Are there any diseases or disorders associated with ARPP21 dysfunction?

At this point, there is no specific information linking ARPP21 dysfunction to any particular diseases or disorders. However, further research is needed to fully understand its role and potential implications.

Can ARPP21 be used as a therapeutic target?

Currently, there is no direct evidence suggesting that ARPP21 can be targeted for therapeutic purposes. However, continued research may reveal its potential as a target for certain conditions in the future.

What are some research areas related to ARPP21?

Researchers are exploring the functions and mechanisms of ARPP21, its role in synaptic plasticity and cognitive processes, as well as its potential involvement in neurological disorders such as schizophrenia and addiction.

Are there any known interacting partners of ARPP21?

Yes, some studies suggest that ARPP21 interacts with other molecules or proteins involved in cellular signaling pathways, such as protein phosphatase 2A (PP2A), which is involved in regulating protein phosphorylation.

Where can I find more information about ARPP21?

To find more information about ARPP21 and its current research, you can refer to scientific journals, databases like PubMed, or academic websites specializing in neuroscience or protein research.