Recombinant Human ART3 protein, GST-tagged
Cat.No. : | ART3-869H |
Product Overview : | Human ART3 full-length ORF ( AAH08397, 27 a.a. - 389 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 65.67 kDa |
AA Sequence : | EVLDMADNAFDDEYLKCTDRMEIKY VPQLLKEEKASHQQLDTVWENAKAK WAARKTQIFLPMNFKDNHGIALMAY ISEAQEQTPFYHLFSEAVKMAGQSR EDYIYGFQFKAFHFYLTRALQLLRK PCEASSKTVVYRTSQGTSFTFGGLN QARFGHFTLAYSAKPQAANDQLTVL SIYTCLGVDIENFLDKESERITLIP LNEVFQVSQEGAGNNLILQSINKTC SHYECAFLGGLKTENCIENLEYFQP IYVYNPGEKNQKLEDHSEKNWKLED HGEKNQKLEDHGVKILEPTQIPGMK IPEPFPLPEDKSQGNINNPTPGPVP VPGPKSHPSASLGKLLLPQFGMVII LISVSAINLFVAL |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ART3 ADP-ribosyltransferase 3 [ Homo sapiens ] |
Official Symbol : | ART3 |
Synonyms : | ART3; ADP-ribosyltransferase 3; ecto-ADP-ribosyltransferase 3; mono-ADP-ribosyltransferase; mono(ADP-ribosyl)transferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3; FLJ26404; |
Gene ID : | 419 |
mRNA Refseq : | NM_001130016 |
Protein Refseq : | NP_001123488 |
MIM : | 603086 |
UniProt ID : | Q13508 |
Products Types
◆ Recombinant Protein | ||
ART3-764M | Recombinant Mouse ART3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ART3-64C | Recombinant Cynomolgus Monkey ART3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ART3-314C | Recombinant Cynomolgus ART3 Protein, His-tagged | +Inquiry |
ART3-569H | Recombinant Human ART3, His tagged | +Inquiry |
ART3-1990M | Recombinant Mouse ART3 Protein | +Inquiry |
◆ Lysates | ||
ART3-1148HCL | Recombinant Human ART3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionART3 ADP-ribosylates specific arginine residues on target proteins, including CD28, a critical co-stimulatory molecule in T cell activation.
Mutations in the ART3 gene have not been directly linked to specific diseases or disorders in humans so far.
The precise regulation of ART3 gene expression is not well characterized, but it may be influenced by various cellular and immune signaling pathways.
ART3 activity depends on the availability of NAD+ as a substrate and can also be influenced by various cellular signaling pathways related to immune responses.
Dysregulated ADP-ribosylation, including ART3 activity, has been implicated in various diseases. However, the specific role of ART3 in these conditions requires further investigation.
Animal models, such as ART3 knockout mice, have been generated to investigate the role of ART3 in vivo, providing insights into its physiological functions.
ART3 transfers ADP-ribose from NAD+ to specific target proteins, modifying their structure and function.
Customer Reviews (3)
Write a reviewThe ART3 Protein boasts remarkable stability, ensuring its integrity is maintained during storage and experimentation.
One remarkable aspect of the ART3 Protein is the outstanding technical support provided by the manufacturer.
Equally noteworthy is the remarkable technical support provided by the manufacturer.
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