Recombinant Human ARV1 protein, GST-tagged

• Cat.No.: ARV1-874H
• Product Overview: Human ARV1 full-length ORF ( NP_073623.1, 1 a.a. - 271 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transmembrane protein that contains a conserved zinc ribbon motif at the N- terminus. A similar protein in mouse is thought to function in fatty acid homeostasis. Mutations in this gene are associated with early infantile epileptic encephalopathy 38. [provided by RefSeq, Nov 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.5 kDa
• AA Sequence: MGNGGRSGLQQGKGNVDGVAATPTA ASASCQYRCIECNQEAKELYRDYNH GVLKITICKSCQKPVDKYIEYDPVI ILINAILCKAQAYRHILFNTQINIH GKLCIFCLLCEAYLRWWQLQDSNQN TAPDDLIRYAKEWDFYRMFAIAALE QTAYFIGIFTFLWVERPMTAKKKPN FILLLKALLLSSYGKLLLIPAVIWE HDYTSVCLKLIKVFVLTSNFQAIRV TLNINRKLSFLAVLSGLLLESIMVY FFQSMEWDVGSDYAIFKSQDF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARV1 ARV1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ARV1
• Synonyms: ARV1; ARV1 homolog, fatty acid homeostasis modulator; EIEE38; protein ARV1
• Gene ID: 64801
• mRNA Refseq: NM_022786.1
• Protein Refseq: NP_073623.1
• MIM: 611647
• UniProt ID: Q9H2C2

Reviews

08/17/2021

Their expertise and assistance have been invaluable in troubleshooting and providing insightful solutions, greatly enhancing the progress of my experiments.

06/23/2019

What further sets the ARV1 Protein apart is the outstanding technical support provided by the manufacturer.

06/20/2016

They have proven to be a timely and reliable resource, readily addressing any concerns or challenges that arise during my research.

Q&As

Does the ARV1 protein have any enzymatic activity?

The ARV1 protein does not possess any known enzymatic activity.

Are there any known diseases associated with mutations in the ARV1 gene?

Mutations in the ARV1 gene have been linked to a human neurological disorder known as hereditary sensory and autonomic neuropathy type 2 (HSAN2).

Can the ARV1 protein affect cell growth and viability?

es, the ARV1 protein is essential for cell growth and viability in yeast cells.

Is the expression of the ARV1 gene tissue-specific?

The ARV1 gene is expressed in a wide range of tissues, indicating its importance in various cellular processes.

Can the ARV1 protein modulate the sensitivity of cells to antifungal drugs?

Yes, the ARV1 protein has been found to modulate sensitivity to certain antifungal drugs, including Amphotericin B.

Is the ARV1 protein conserved across different organisms?

Yes, the ARV1 protein is highly conserved from yeast to mammals, indicating its important physiological role.

Can the ARV1 protein interact with other proteins or lipids?

Yes, the ARV1 protein interacts with certain lipid molecules and other proteins involved in lipid metabolism and membrane biogenesis.

Does the ARV1 protein play a role in cholesterol metabolism?

Yes, the ARV1 protein is involved in cholesterol metabolism, specifically in regulating the transport and metabolism of sterols in the ER.