Recombinant Human ASB16 protein, GST-tagged

• Cat.No.: ASB16-888H
• Product Overview: Human ASB16 full-length ORF (BAG37167.1, 1 a.a. - 453 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.23 kDa
• AA Sequence: MARETFPFTSSMLRSLRLQQEWLEW EDRRRAAAQQCRSRRCPSSPRARLT RPHRSCRDPAVHHALFSGNLQQVQA LFQDEEAANMIVETVSNQLAWSAEQ GFWVLTPKTKQTAPLAIATARGYTD CARHLIRQGAELDARVGGRAALHEA CARAQFDCVRLLLTFGAKANVLTEE GTTPLHLCTIPESLQCAKLLLEAGA TVNLAAGESQETPLHVAAARGLEQH VALYLEHGADVGLRTSQGETALNAA CAGAEGPGSCRRHQAAARRLLEAGA DARAAGRKRHTPLHNACASGCGGLA ELLLRYGARAEVPNGAGHTPMDCAL QAVQDAPNWEPEVLFAALLDYGAQP VRPEMLKHCANFPRALEVLLNAYPC VPSCETWVEAVLPELWKEHEAFYSS ALCMVNQPRQLQHLARLAVRARLGS RCRQGATRLPLPPLLRDYLLLRVEG CIQ
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASB16 ankyrin repeat and SOCS box containing 16 [ Homo sapiens (human) ]
• Official Symbol: ASB16
• Synonyms: ASB16; ankyrin repeat and SOCS box containing 16; ankyrin repeat and SOCS box protein 16; ankyrin repeat and SOCS box-containing protein 16
• Gene ID: 92591
• mRNA Refseq: NM_080863
• Protein Refseq: NP_543139
• MIM: 615056
• UniProt ID: Q96NS5

Reviews

03/14/2020

In addition to its advantages in trials, the manufacturer of the ASB16 protein offers exceptional support to researchers.

12/17/2018

Its high specificity and functional integrity ensure accurate and reproducible data, allowing researchers to draw meaningful conclusions from their experiments.

04/15/2016

the ASB16 protein has been extensively studied and validated in various experimental applications.

Q&As

Are there any known small molecules or drugs that can modulate ASB16 activity?

Currently, there are no known small molecules or drugs specifically designed to modulate ASB16 activity. It is an active area of research for potential therapeutic interventions.

Are there any known interactions of the ASB16 protein with other proteins?

Yes, the ASB16 protein has been shown to interact with certain proteins involved in cellular signaling pathways, such as components of the ubiquitin-proteasome system.

Are there any genetic variations or polymorphisms in the ASB16 gene?

Yes, several genetic variations and polymorphisms have been identified in the ASB16 gene, which may have implications in certain diseases and conditions.

Does ASB16 have any known substrates for protein degradation?

The specific substrates targeted by ASB16 for protein degradation have not been fully identified yet.

In which tissues or organs is the ASB16 protein expressed?

The ASB16 protein is expressed in various tissues and organs, including the brain, heart, liver, and skeletal muscle.

Is ASB16 expression regulated by environmental factors?

The regulation of ASB16 expression by environmental factors has not been extensively studied, but it is possible that certain environmental cues might influence its expression.

Is ASB16 involved in any specific cellular pathways or processes?

The ASB16 protein is believed to be involved in various cellular processes, including protein degradation, intracellular signaling, and potentially neuronal development.