Recombinant Human ASCL5 Protein, His (Fc)-Avi-tagged

• Cat.No.: ASCL5-2504H
• Product Overview: Recombinant Human ASCL5 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ASCL5 achaete-scute complex homolog 5 (Drosophila) [ Homo sapiens ]
• Official Symbol: ASCL5
• Gene ID: 647219
• mRNA Refseq: NM_001270601.1
• Protein Refseq: NP_001257530.1

Reviews

08/01/2019

Its purity and consistency have consistently generated trustworthy and reproducible results in my research.

04/10/2019

Their proactive approach ensures that I am always working with the latest advancements in ASCL5 protein research, allowing me to explore new avenues and potentially uncover groundbreaking discoveries.

03/04/2018

The combination of exceptional quality, reliable performance, and dedicated customer service makes them an invaluable partner in my research journey.

Q&As

How does ASCL5 regulate cell fate determination?

ASCL5 functions as a transcription factor, binding to specific DNA sequences in target genes and regulating their expression. By activating or repressing target genes, ASCL5 controls the differentiation of intestinal progenitor cells into various cell types, such as absorptive enterocytes and secretory cells.

Are there any known genetic variations or mutations in the ASCL5 gene?

Limited information is available regarding genetic variations or mutations in the ASCL5 gene. Further research is required to understand the potential influence of such variations on gastrointestinal development or related disorders.

Can ASCL5 be targeted for therapeutic purposes?

As ASCL5 is involved in crucial developmental processes, targeting it directly for therapeutic purposes may be challenging. However, understanding the mechanisms and pathways regulated by ASCL5 could help identify potential drug targets to treat gastrointestinal disorders or promote tissue regeneration.

Does ASCL5 have any known roles outside of the gastrointestinal tract?

While ASCL5 is primarily associated with gastrointestinal development, recent studies suggest potential roles for this protein in other tissues, such as the lung and pancreas. However, the extent and significance of these roles are still being investigated.