Recombinant Human ATG4C Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ATG4C-2548H |
Product Overview : | ATG4C MS Standard C13 and N15-labeled recombinant protein (NP_116241) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 52.3 kDa |
AA Sequence : | MEATGTDEVDKLKTKFISAWNNMKY SWVLKTKTYFSRNSPVLLLGKCYHF KYEDEDKTLPAESGCTIEDHVIAGN VEEFRKDFISRIWLTYREEFPQIEG SALTTDCGWGCTLRTGQMLLAQGLI LHFLGRAWTWPDALNIENSDSESWT SHTVKKFTASFEASLSGEREFKTPT ISLKETIGKYSDDHEMRNEVYHRKI ISWFGDSPLALFGLHQLIEYGKKSG KKAGDWYGPAVVAHILRKAVEEARH PDLQGITIYVAQDCTVYNSDVIDKQ SASMTSDNADDKAVIILVPVRLGGE RTNTDYLEFVKGILSLEYCVGIIGG KPKQSYYFAGFQDDSLIYMDPHYCQ SFVDVSIKDFPLETFHCPSPKKMSF RKMDPSCTIGFYCRNVQDFKRASEE ITKMLKFSSKEKYPLFTFVNGHSRD YDFTSTTTNEEDLFSEDEKKQLKRF STEEFVLLTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ATG4C autophagy related 4C cysteine peptidase [ Homo sapiens (human) ] |
Official Symbol : | ATG4C |
Synonyms : | ATG4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C (S. cerevisiae), APG4C, AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae), AUTL1; cysteine protease ATG4C; AUTL3; FLJ14867; autophagin-3; APG4 autophagy 4 homolog C; AUT-like 3 cysteine endopeptidase; AUT-like 1, cysteine endopeptidase; autophagy-related protein 4 homolog C; autophagy-related cysteine endopeptidase 3; APG4C; AUTL1; APG4-C; |
Gene ID : | 84938 |
mRNA Refseq : | NM_032852 |
Protein Refseq : | NP_116241 |
MIM : | 611339 |
UniProt ID : | Q96DT6 |
Products Types
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◆ Lysates | ||
ATG4C-8623HCL | Recombinant Human ATG4C 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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