Recombinant Human ATRN, His-tagged

• Cat.No.: ATRN-3774H
• Product Overview: Attractin (ATRN), partial

Specification

• Description: Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 1156
• Purity: >90%
• Notes: Small volumes of ATRN recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ATRN attractin [ Homo sapiens ]
• Official Symbol: ATRN
• Synonyms: ATRN; attractin; DPPT L; mahogany protein; MGCA; attractin-2; mahogany homolog; DPPT-L; KIAA0548; MGC126754
• Gene ID: 8455
• mRNA Refseq: NM_001207047
• Protein Refseq: NP_001193976
• MIM: 603130
• UniProt ID: O75882
• Chromosome Location: 20p13
• Function: binding; receptor activity; sugar binding

Reviews

11/13/2022

ATRN's exceptional purity ensures accurate and reproducible experimental results.

07/07/2022

The protein manufacturer's products are backed by strong scientific research and development to provide customers with cutting-edge solutions.

03/04/2022

Because ATRN is resistant to degradation and its stability under various experimental conditions makes it the best choice for Western blot analysis.

Q&As

What diseases or symptoms can be caused by ATRN mutations?

ATRN gene mutations may lead to hereditary hemorrhagic telangiectasia and other diseases. The main features of the disease include telangiectasia on the skin and mucosa, epistaxis, and bleeding in internal organs.

Are there other genes that interact with the ATRN gene?

Yes, the ATRN gene may interact with other genes involved in the regulation of cell development and function, such as the Netrin-1 gene in nervous system development. These interactions may affect the function and regulatory network of ATRN genes.

Is the ATRN gene regulated?

Yes, ATRN gene expression is affected by a variety of regulatory factors, including binding of transcription factors, activation of signaling pathways, etc. These regulatory mechanisms ensure the adaptability and stability of the ATRN gene.

Is ATRN gene associated with cancer?

At present, no direct association between ATRN gene and cancer has been found. However, the regulatory role of ATRN genes in cell proliferation and differentiation may be indirectly related to tumorigenesis and progression.

What is the expression pattern of ATRN gene?

The ATRN gene is widely expressed in the human body, but its expression level may vary in different tissues and organs. Its expression is higher in brain, retina, kidney and other tissues.

What progress has been made in the research of ATRN gene?

The research on ATRN gene mainly focuses on the analysis of its structure and function, the exploration of its regulatory mechanism, and the relationship with genetic diseases. So far, several important findings have been made regarding the function and regulation of ATRN genes.