Recombinant Human ATXN7L1 293 Cell Lysate

• Cat.No.: ATXN7L1-8565HCL

Specification

• Description: Antigen standard for ataxin 7-like 1 (ATXN7L1), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: ATXN7L1 ataxin 7-like 1 [ Homo sapiens ]
• Official Symbol: ATXN7L1
• Synonyms: ATXN7L1; ataxin 7-like 1; ataxin 7 like 4 , ATXN7L4; KIAA1218; MGC33190
• Gene ID: 57485
• UniProt ID: Q9ULK2
• Chromosome Location: 7q22.1

Reviews

04/15/2021

Unusual activity of ATXN7L1 under a variety of conditions highlights its robustness and versatility.

10/10/2020

This extraordinary repeatability of ATXN7L1 under various conditions highlights its robustness and versatility.

03/27/2019

The exceptional purity of ATXN7L1 under various conditions highlights its robustness and versatility.

Q&As

In which cell types is ATXN7Lprotein found?

ATXN7L protein may be expressed in a variety of cell types, but its specific distribution may vary by tissue type and developmental stage.

Are there drugs or therapies that can modulate the activity of ATXN7Lprotein?

There may currently be drug studies targeting the Ataxin family or related pathways, but the specific drugs may vary by disease and treatment target.

Are there diseases associated with ATXN7Lprotein?

Mutations associated with Ataxin family proteins may be associated with certain neurodegenerative diseases.

How does ATXN7Laffect cell function?

Due to the interaction with other molecules, ATXN7L1 protein may affect various cellular functions, such as gene expression regulation.

In what biological processes does ATXN7Lprotein function?

The specific biological processes may include gene transcriptional regulation, protein homeostasis, and cell signaling, among others.

What is the basic structure of ATXN71L protein?

The specific structure of the ATXN7L1 protein may include multiple functional domains, such as protein interaction domains and possibly nuclear localization signals.