Recombinant Human AURKB protein, His-tagged
Cat.No. : | AURKB-3924H |
Product Overview : | Recombinant Human AURKB protein(1-371 aa), fused to His tag, was expressed in E. coli. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein Length : | 1-371 aa |
AA Sequence : | QIQLFAGGRESSSALDPSSPPPFSL RMAQKENSYPWPYGRQTAPSGLSTL PQRVLRKEPVTPSALVLMSRSNVQP TAAPGQKVMENSSGTPDILTRRHFT IDDFEIGRPLGKGKFGNVYLAREKK SHFIVALKVLFKSQIEKEGVEHQLR REIEIQAHLHHPNILRLYNYFYDRR RIYLILEYAPRGELYKELQKSCTFD EQRTATIMEELADALMYCHGKKVIH RDIKPENLLLGLKGELKIADFGWSV HAPSLRRKTMCGTLDYLPPEMIEGR MHNEKVDLWCIGVLCYELLVGNPPF ESASHNETYRRIVKVDLKFPASVPM GAQDLISKLLRHNPSERLPLAQVSA HPWVRANSRRVLPPSALQSVA |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | AURKB aurora kinase B [ Homo sapiens ] |
Official Symbol : | AURKB |
Synonyms : | AURKB; aurora kinase B; serine/threonine kinase 12 , STK12; Aik2; AIM 1; ARK2; AurB; aurora 1; aurora B; IPL1; PPP1R48; protein phosphatase 1; regulatory subunit 48; STK5; ARK-2; STK-1; aurora-1; aurora-B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora-related kinase 2; serine/threonine kinase 12; aurora/IPL1-related kinase 2; serine/threonine-protein kinase 5; serine/threonine-protein kinase 12; serine/threonine-protein kinase aurora-B; protein phosphatase 1, regulatory subunit 48; aurora- and Ipl1-like midbody-associated protein 1; AIK2; AIM1; AIM-1; STK12; aurkb-sv1; aurkb-sv2; |
Gene ID : | 9212 |
mRNA Refseq : | NM_001256834 |
Protein Refseq : | NP_001243763 |
MIM : | 604970 |
UniProt ID : | Q96GD4 |
Products Types
◆ Recombinant Protein | ||
AURKB-1113H | Recombinant Human AURKB Protein (A2-A344), GST tagged | +Inquiry |
Aurkb-1789M | Recombinant Mouse Aurkb Protein, Myc/DDK-tagged | +Inquiry |
AURKB-1112H | Recombinant Human AURKB Protein (A2-A344), Tag Free | +Inquiry |
AURKB-909M | Recombinant Mouse AURKB Protein, His (Fc)-Avi-tagged | +Inquiry |
Aurkb-279R | Recombinant Rat Aurkb Protein, His-tagged | +Inquiry |
◆ Lysates | ||
AURKB-8560HCL | Recombinant Human AURKB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionAURKB protein interacts with a variety of cell cycle regulatory proteins, including Cdk1, INCENP, Survivin, etc., to regulate the progression of cell mitosis.
The substrates of AURKB include chromosome-associated proteins, cytoskeletal proteins and other cell cycle regulatory proteins. Phosphorylation modification of these substrates regulates chromosome segregation and cell division during mitosis.
AURKB protein is mainly located in the nucleus and cytoplasm and participates in the regulation of cell mitosis.
The expression of the AURKB gene is regulated by cell cycle regulators and other transcription factors and is mainly expressed in the mitotic phase of cells.
The activity of AURKB protein is regulated by a variety of factors, including phosphorylation modification, protein interaction and cell cycle regulation.
The protein reaches its peak expression during early and metaphase of cell mitosis and is closely associated with chromosome segregation and cell division.
Customer Reviews (3)
Write a reviewAURKB's exceptional repeatability allows for its reliable use in a range of applications, making it a top choice for researchers.
Very pure and can be used with confidence.
The quality is very high and very reliable.
Ask a Question for All AURKB Products
Required fields are marked with *
My Review for All AURKB Products
Required fields are marked with *
Inquiry Basket