Recombinant Human Aurora Kinase A
Cat.No. : | AURKA-655H |
Product Overview : | Recombinant Human Aurora Kinase A is produced inEscherichia coli.MW=80 kDa. |
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Cat. No. : | AURKA-655H |
Description : | Aurora A kinase also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora A is activated by one or more phosphorylations and its activity peaks during the G2 phase to M phase transition in the cell cycle. |
Source : | E.coli. |
Purity : | >85% (SDS-PAGE). |
Form : | Aqueous glycerol solution. |
Storage : | −70°C. Shipped in wet ice. |
Gene Name : | RLN1 relaxin 1 [ Homo sapiens ] |
Synonyms : | AURKA; aurora kinase A; ARK-1; IPL1-related kinase; OTTHUMP00000031341; OTTHUMP00000166072; aurora-related kinase 1; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; breast tumor-amplified kinase; breast-tumor-amplified kinase; hARK1; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A |
Gene ID : | 6790 |
mRNA Refseq : | NM_006911 |
Protein Refseq : | NP_008842 |
MIM : | 179730 |
UniProt ID : | P04808 |
Chromosome Location : | 20q13.2-q13.3 |
Function : | hormone activity |
Products Types
◆ Recombinant Protein | ||
AURKA-411H | Recombinant Human AURKA Protein, His (Fc)-Avi-tagged | +Inquiry |
AURKA-907M | Recombinant Mouse AURKA Protein, His (Fc)-Avi-tagged | +Inquiry |
AURKA-0694H | Recombinant Human AURKA Protein (D2-S403), Tag Free | +Inquiry |
AURKA-11H | Active Recombinant Human AURKA Protein (2-403), N-His tagged | +Inquiry |
Aurka-1788M | Recombinant Mouse Aurka Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
AURKA-8563HCL | Recombinant Human AURKA 293 Cell Lysate | +Inquiry |
AURKA-8564HCL | Recombinant Human AURKA 293 Cell Lysate | +Inquiry |
AURKA-8562HCL | Recombinant Human AURKA 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionAURKA protein interacts with a variety of cell cycle regulatory proteins, including Cdk1, Plk1, TPX2, etc., to regulate the progression of cell cycle.
The protein plays an important role in the G2 and M phases of the cell cycle and is involved in the regulation of nuclear division, chromosome segregation, and cell mitosis.
AURKA protein may be involved in the regulation of apoptosis and DNA damage repair, but the specific mechanism needs to be further studied.
The activity is regulated by a variety of factors, including phosphorylation modification, protein interaction and cell cycle regulation.
It is mainly localized in the cytoplasm and nucleus and is involved in cell cycle regulation and cell division processes.
This protein plays an important role in tumorigenesis, and its overexpression or mutation may lead to abnormal cell proliferation, chromosome instability and tumorigenesis.
Customer Reviews (3)
Write a reviewAURKA's exceptional stability allows for its reliable use in a range of applications, making it a top choice for researchers.
This protein's exceptional activity allows for its reliable use in a range of applications, making it a top choice for researchers.
Due to the extensive storage conditions of proteins, the experimental process is more stable and reliable, which provides a strong guarantee for scientific research.
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