| Description : |
This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
131.7 kDa |
| AA Sequence : |
MRPRGAAFAAGPPGDLHLGTAIGFA GAIWRSRSPAMSTLLDIKSSVLRQV QVCPSFRRRTEQDPGSASADPQEPA TGAWKPGDGVEFFAHMRLMLKKGEG RQGLPCLEVPLRSGSPAPPEPVDPS LGLRALAPEEVEMLYEEALYTVLYR AGTMGPDQVDDEEALLSYLQQVFGT SLEEHTEAIERVRKAKAPTYALKVS VMRAKNLLAKDPNGFSDPYCMLGIL PASDATREPRAQKEQRFGFRKGSKR GGPLPAKCIQVTEVKSSTLNPVWKE HFLFEIEDVSTDQLHLDIWDHDDDV SLVEACRKLNEVIGLKGMGRYFKQI VKSARANGTAGPTEDHTDDFLGCLN IPVREVPVAGVDRWFKLEPRSSASR VQGHCHLVLKLITTQRDTAMSQRGR SGFLSHLLLLSHLLRLEHSAEEPNS SSWRGELSTPAATILCLHGAQSNLS PLQLAVLHWQVSSRHHQTCTLDYSY LLGLLEDMQAHWEEAPSLPQEQEES LADSLSAFSEFGLQLLRQLRDYFPA TNSTAVHRLELLLKCLGKLQLFQPS FEICPFESELNMDIAAALKRGNREW YDRILNDKSPREQPGPQRLPGLVVL ADAVYDDLQFCYSVYASLFHSILNV DVFTLTFRQLERLVAEEAWVLTEEL SPKMTLEVASGLFELYLTLADLQRF WDSIPGRDSRSLALAGIHAPFLPAV KLWFQVLRDQAKWRLQGAVDMDTLE PVDASSRHSSSAATAGLCLSHIQEL WVRLAWPDPAQAQGLGTQLGQDVCE ATLFYTELLRKKVDTQPGAAGEAVS EALCVVLNNVELVRKAAGQALKGLA WPEGATGPEGVLPRPLLSCTQALDD DLQREAHTVTAHLTSKMVGDIRKYV QHISLSPDSIQNDEAVAPLMKYLDE KLALLNASLVKGNLSRVLEALWELL LQAILQALGANRDVSADFYSRFHFT LEALVSFFHAEGQGLPLESLRDGSY KRLKEELRLHKCSTRECIEQFYLDK LKQRTLEQNRFGRLSVRCHYEAAEQ RLAVEVLHAADLLPLDANGLSDPFV IVELGPPHLFPLVRSQRTQVKTRTL HPVYDELFYFSVPAEACRRRAACVL FTVMDHDWLSTNDFAGEAALGLGGV TGVARPQVGGGARAGQPVTLHLCRP RAQVRSALRRLEGRTSKEAQEFVKK LKELEKCMEADPTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
