Recombinant Human BBOX1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BBOX1-6335H
• Product Overview: BBOX1 MS Standard C13 and N15-labeled recombinant protein (NP_003977) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 44.7 kDa
• AA Sequence: MACTIQKAEALDGAHLMQILWYDEE ESLYPAVWLRDNCPCSDCYLDSAKA RKLLVEALDVNIGIKGLIFDRKKVY ITWPDEHYSEFQADWLKKRCFSKQA RAKLQRELFFPECQYWGSELQLPTL DFEDVLRYDEHAYKWLSTLKKVGIV RLTGASDKPGEVSKLGKRMGFLYLT FYGHTWQVQDKIDANNVAYTTGKLS FHTDYPALHHPPGVQLLHCIKQTVT GGDSEIVDGFNVCQKLKKNNPQAFQ ILSSTFVDFTDIGVDYCDFSVQSKH KIIELDDKGQVVRINFNNATRDTIF DVPVERVQPFYAALKEFVDLMNSKE SKFTFKMNPGDVITFDNWRLLHGRR SYEAGTEISRHLEGAYADWDVVMSR LRILRQRVENGNTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BBOX1 gamma-butyrobetaine hydroxylase 1 [ Homo sapiens (human) ]
• Official Symbol: BBOX1
• Synonyms: BBOX1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; BBOX; gamma-butyrobetaine dioxygenase; BBH; G BBH; gamma BBH; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1; G-BBH; gamma-BBH
• Gene ID: 8424
• mRNA Refseq: NM_003986
• Protein Refseq: NP_003977
• MIM: 603312
• UniProt ID: O75936