Recombinant Human BCAT1 Protein, GST-tagged

• Cat.No.: BCAT1-129H
• Product Overview: Human BCAT1 full-length ORF ( AAH33864, 1 a.a. - 320 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 60.94 kDa
• AA Sequence: MDCSNGCSAECTGEGGSKEVVGTFK AKDLIVTPATILKEKPDPNNLVFGT VFTDHMLTVEWSSEFGWEKPHIKPL QNLSLHPGSSALHYAVELFEGLKAF RGVDNKIRLFQPNLNMDRMYRSAVR ATLPVFDKEELLECIQQLVKLDQEW VPYSTSASLYIRPTFIGTEPSLGVK KPTKALLFVLLSPVGPYFSSGTFNP VSLWANPKYVRAWKGGTGDCKMGGN YGSSLFAQCEAVDNGCQQVLWLYGE DHQITEVGTMNLFLYWINEDGEEEL ATPPLDGIILPGVTRRCILDLAHQW DTELSLFSINLPDFLQFIYF
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCAT1 branched chain amino-acid transaminase 1, cytosolic [ Homo sapiens ]
• Official Symbol: BCAT1
• Synonyms: BCAT1; branched chain amino-acid transaminase 1, cytosolic; BCT1, branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; branched chain aminotransferase 1, cytosolic; BCT1; PP18; BCATC; ECA39; MECA39; PNAS121; DKFZp686E12175
• Gene ID: 586
• mRNA Refseq: NM_001178091
• Protein Refseq: NP_001171562
• MIM: 113520
• UniProt ID: P54687