Recombinant human BEND6, His-tagged
Cat.No. : | BEND6-2441H |
Product Overview : | Recombinant human BEND6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | BEND6, as known as BEN domain-containing protein 6, is a neural BEN-solo factor that shares many functional attributes with Drosophila Insensitive, a co-repressor for the Drosophila CSL factor. This protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. In addition, its association with Notch- and CBF1-regulated enhancers is promoted by CBF1 and antagonized by activated Notch. In utero electroporation experiments showed that ectopic BEND6 inhibited Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl |
Molecular Mass : | 33.6kDa (302aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSKEELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSSPVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTNEYMA THSLTGAKSS TSRDKAVKPA MNQNEVQEII GVTKQLFPNTDDVSIRRMIG QKLNNCTKKP NLSKNLNSQD IK |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | BEND6 BEN domain containing 6 [ Homo sapiens ] |
Official Symbol : | BEND6 |
Synonyms : | BEND6; BEN domain containing 6; C6orf65, chromosome 6 open reading frame 65; BEN domain-containing protein 6; bA203B9.1; FLJ30162; C6orf65; |
Gene ID : | 221336 |
mRNA Refseq : | NM_152731 |
Protein Refseq : | NP_689944 |
UniProt ID : | Q5SZJ8 |
Chromosome Location : | 6p12.1 |
Products Types
◆ Recombinant Protein | ||
Bend6-1858M | Recombinant Mouse Bend6 Protein, Myc/DDK-tagged | +Inquiry |
BEND6-1010M | Recombinant Mouse BEND6 Protein, His (Fc)-Avi-tagged | +Inquiry |
BEND6-2422H | Recombinant Human BEND6 Protein, MYC/DDK-tagged | +Inquiry |
BEND6-359R | Recombinant Rhesus Macaque BEND6 Protein, His (Fc)-Avi-tagged | +Inquiry |
BEND6-531R | Recombinant Rhesus monkey BEND6 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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