Recombinant Human BEST1, GST-tagged
Cat.No. : | BEST1-10208H |
Product Overview : | Recombinant Human BEST1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-180a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | BEST1 bestrophin 1 [ Homo sapiens ] |
Official Symbol : | BEST1 |
Synonyms : | BEST1; bestrophin 1; vitelliform macular dystrophy 2 , VMD2; bestrophin-1; BEST; Best disease; BMD; vitelliform macular dystrophy protein 2; ARB; RP50; VMD2; TU15B; |
Gene ID : | 7439 |
mRNA Refseq : | NM_001139443 |
Protein Refseq : | NP_001132915 |
MIM : | 607854 |
UniProt ID : | O76090 |
Chromosome Location : | 11q12 |
Function : | chloride channel activity; contributes_to chloride channel activity; ion channel activity; |
Products Types
◆ Recombinant Protein | ||
Best1-1859M | Recombinant Mouse Best1 Protein, Myc/DDK-tagged | +Inquiry |
BEST1-1012M | Recombinant Mouse BEST1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BEST1-2597H | Recombinant Human BEST1 Protein, MYC/DDK-tagged | +Inquiry |
BEST1-447H | Recombinant Human BEST1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BEST1-90C | Recombinant Cynomolgus Monkey BEST1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BEST1-1910HCL | Recombinant Human BEST1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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