Recombinant Human BMF, His-tagged
Cat.No. : | BMF-26283TH |
Product Overview : | Recombinant full length Human Bmf isoform 3 , fused to 15 amino acid His Tag at the N-terminus, predicted MWt 15.6kDa including the tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Protein length : | 129 amino acids |
Conjugation : | HIS |
Molecular Weight : | 15.600kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 7.50Constituents:0.32% Tris HCl, 0.02% DTT, 10% Glycerol |
Storage : | Please see Notes section |
Sequences of amino acids : | MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSPASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP |
Sequence Similarities : | Belongs to the Bcl-2 family. |
Gene Name : | BMF Bcl2 modifying factor [ Homo sapiens ] |
Official Symbol : | BMF |
Synonyms : | BMF; Bcl2 modifying factor; bcl-2-modifying factor; FLJ00065; |
Gene ID : | 90427 |
mRNA Refseq : | NM_033503 |
Protein Refseq : | NP_277038 |
MIM : | 606266 |
Uniprot ID : | Q96LC9 |
Chromosome Location : | 15q14 |
Pathway : | Activation of BH3-only proteins, organism-specific biosystem; Activation of BMF and translocation to mitochondria, organism-specific biosystem; Apoptosis, organism-specific biosystem; Intrinsic Pathway for Apoptosis, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
Bmf-1879M | Recombinant Mouse Bmf Protein, Myc/DDK-tagged | +Inquiry |
BMF-652R | Recombinant Rat BMF Protein, His (Fc)-Avi-tagged | +Inquiry |
BMF-515H | Recombinant Human BMF protein(Met1-Arg184), His-tagged | +Inquiry |
BMF-4721H | Recombinant Human BMF protein, GST-tagged | +Inquiry |
BMF-994R | Recombinant Rat BMF Protein | +Inquiry |
◆ Lysates | ||
BMF-8438HCL | Recombinant Human BMF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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