Recombinant Human BMF, T7 -tagged
Cat.No. : | BMF-27487TH |
Product Overview : | Recombinant full length Human Bmf isoform 3 , with N terminal T7 tag, Predicted MWt 15.6 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Conjugation : | T7 |
Source : | E. coli |
Tissue specificity : | Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP |
Sequence Similarities : | Belongs to the Bcl-2 family. |
Gene Name : | BMF Bcl2 modifying factor [ Homo sapiens ] |
Official Symbol : | BMF |
Synonyms : | BMF; Bcl2 modifying factor; bcl-2-modifying factor; FLJ00065; |
Gene ID : | 90427 |
mRNA Refseq : | NM_033503 |
Protein Refseq : | NP_277038 |
MIM : | 606266 |
Uniprot ID : | Q96LC9 |
Chromosome Location : | 15q14 |
Pathway : | Activation of BH3-only proteins, organism-specific biosystem; Activation of BMF and translocation to mitochondria, organism-specific biosystem; Apoptosis, organism-specific biosystem; Intrinsic Pathway for Apoptosis, organism-specific biosystem; |
Function : | protein binding; |
Products Types
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◆ Lysates | ||
BMF-8438HCL | Recombinant Human BMF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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