Recombinant Human BMP4 Protein, His-MBP-tagged

• Cat.No.: BMP4-001H
• Product Overview: Recombinant Human BMP4 Protein 25-408 aa (full-length) with His-MBP tag was expressed in E.coli.

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
• Source: E. coli
• Species: Human
• Tag: His-MBP
• Molecular Mass: 90.2 kDa
• Purity: >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB)
• Applications: ELISA, WB, Antibody Production, Protein array
• Quality Control Test: 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-MBP (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry.
• Storage: Store working aliquots at 4 centigrade for up to one week.
  For extended storage, conserve at −80 centigrade.
• Expiry: 12 months from the date of purchase, if it is properly stored.
• Storage Buffer: 20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole and 30% glycerol, pH 7.4. No preservatives added.
• Shipping: Dry Ice

Gene Information

• Gene Name: BMP4 bone morphogenetic protein 4 [ Homo sapiens (human) ]
• Official Symbol: BMP4
• Synonyms: BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; bone morphogenetic protein 4; bone morphogenetic protein 2B
• Gene ID: 652
• mRNA Refseq: NM_001202
• Protein Refseq: NP_001193
• MIM: 112262
• UniProt ID: P12644