Recombinant Human BMPER protein, His & T7-tagged

• Cat.No.: BMPER-1685H
• Product Overview: Recombinant Human BMPER aa. (Ser40~Cys289 (Accession # Q8N8U9)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.0kDa
• Protein length: Ser40~Cys289 (Accession # Q8N8U9)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6

Gene Information

• Gene Name: BMPER BMP binding endothelial regulator [ Homo sapiens (human) ]
• Official Symbol: BMPER
• Synonyms: BMPER; BMP binding endothelial regulator; CV2; CV-2; CRIM3; BMP-binding endothelial regulator protein; BMP-binding endothelial regulator precursor protein; bone morphogenetic protein-binding endothelial cell precursor-derived regulator; crossveinless 2; hCV2
• Gene ID: 168667
• mRNA Refseq: NM_133468.4
• Protein Refseq: NP_597725.1
• UniProt ID: Q8N8U9