Recombinant Human BRWD1, His&FLAG-tagged
Cat.No. : | BRWD1-38H |
Product Overview : | Recombinant Human BRWD1 corresponding to amino acids 1310-1430 that contains the bromodomain sequences of BRWD1 (accession number NP_061836.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag. |
- Specification
- Gene Information
- Related Products
Description : | Bromodomain and WD repeat domain containing 1 (BRWD1), also known as WDR9 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. The bromodomain functions as a "reader" of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. In mouse, this BRWD1 is a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain. This domain associates with a component of the SWI/SNF chromatin remodeling complex and may function to regulate chromatin remodeling. BRWD1 plays a role in the regulation of cell morphology and cytoskeletal organization and is also required in the control of cell shape. |
Source : | E. coli |
Species : | Human |
Tag : | His&FLAG |
Form : | 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol. |
Molecular Mass : | 18.97 kDa |
Applications : | Binding assays, inhibitor screening, and selectivity profiling. |
Storage : | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
Concentration : | 9 mg/ml |
Gene Name : | BRWD1 bromodomain and WD repeat domain containing 1 [ Homo sapiens ] |
Official Symbol : | BRWD1 |
Synonyms : | BRWD1; bromodomain and WD repeat domain containing 1; C21orf107, chromosome 21 open reading frame 107 , WD repeat domain 9 , WDR9; bromodomain and WD repeat-containing protein 1; FLJ11315; N143; transcriptional unit N143; WD repeat protein WDR9-form2; WD repeat-containing protein 9; WDR9; C21orf107; FLJ43918; |
Gene ID : | 54014 |
mRNA Refseq : | NM_001007246 |
Protein Refseq : | NP_001007247 |
UniProt ID : | Q9NSI6 |
Chromosome Location : | 21q22.2 |
Function : | molecular_function; |
Products Types
◆ Recombinant Protein | ||
BRWD1-355H | Recombinant Human BRWD1 Protein, GST-tagged | +Inquiry |
BRWD1-62H | Recombinant Human BRWD1 protein, GST-tagged | +Inquiry |
BRWD1-167H | Recombinant Human BRWD1, GST-tagged | +Inquiry |
BRWD1-63H | Recombinant Human BRWD1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
BRWD1-186HCL | Recombinant Human BRWD1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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