Recombinant Human BTNL2 Protein, Fc-tagged

• Cat.No.: BTNL2-34H
• Product Overview: Recombinant Human BTNL2 Protein, fused to Fc-tag, was expressed in CHO cells.

Specification

• Description: This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
• Source: CHO cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from 0.2μm-filtered solution in PBS, with 5% Mannitol, 5% trehalose.
• Molecular Mass: 75.2 kDa
• AA Sequence: KQSEDFRVIGPAHPILAGVGEDALL TCQLLPKRTTMHVEVRWYRSEPSTP VFVHRDGVEVTEMQMEEYRGWVEWI ENGIAKGNVALKIHNIQPSDNGQYW CHFQDGNYCGETSLLLKVAGLGSAP SIHMEGPGESGVQLVCTARGWFPEP QVYWEDIRGEKLLAVSEHRIQDKDG LFYAEATLVVRNASAESVSCLVHNP VLTEEKGSVISLPEKLQTELASLKV NGPSQPILVRVGEDIQLTCYLSPKA NAQSMEVRWDRSHRYPAVHVYMDGD HVAGEQMAEYRGRTVLVSDAIDEGR LTLQILSARPSDDGQYRCLFEKDDV YQEASLDLKVVSLGSSPLITVEGQE DGEMQPMCSSDGWFPQPHVPWRDME GKTIPSSSQALTQGSHGLFHVQTLL RVTNISAVDVTCSISIPFLGEEKIA TFSLSGWGGGGSGGGGSGGGGSEPR GPTIKPCPPCKCPAPNLLGGPSVFI FPPKIKDVLMISLSPIVTCVVVDVS EDDPDVQISWFVNNVEVHTAQTQTH REDYNSTLRVVSALPIQHQDWMSGK EFKCKVNNKDLPAPIERTISKPKGS VRAPQVYVLPPPEEEMTKKQVTLTC MVTDFMPEDIYVEWTNNGKTELNYK NTEPVLDSDGSYFMYSKLRVEKKNW VERNSYSCSVVHEGLHNHHTTKSFS RTPGK
• Purity: ＞80%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.2mg/tube

Gene Information

• Gene Name: BTNL2 butyrophilin like 2 [ Homo sapiens (human) ]
• Official Symbol: BTNL2
• Synonyms: SS2; BTN7; BTL-II; HSBLMHC1
• Gene ID: 56244
• mRNA Refseq: NM_001304561
• Protein Refseq: NP_001291490
• MIM: 606000
• UniProt ID: Q9UIR0