| Description : |
Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
25.8 kDa |
| AA Sequence : |
MGNCVKYPLRNLSRKMCQEEQTSYM VVQTSEEGLAADAELPGPLLMLAQN CAVMHNLLGPACIFLRKGFAENRQP DRSLRPEEIEELREAFREFDKDKDG YINCRDLGNCMRTMGYMPTEMELIE LSQQINMNLGGHVDFDDFVELMGPK LLAETADMIGVKELRDAFREFDTNG DGEISTSELREAMRKLLGHQVGHRD IEEIIRDVDLNGDGRVDFEEFVRMM SRTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
