Recombinant Human Cathepsin D
Cat.No. : | CTSD-90H |
Product Overview : | Recombinant full length human Catheprsin D protein expressed inE.coli,48kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CTSD-90H |
Description : | Cathepsin D is synthesized as a 54kDa precursor, which is proteolytically processed to an intermediate 48kDa single chain, which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages. |
Source : | E.coli |
Presentation : | 5µg/50µl purified human Cathepsin D protein at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
Applications : | •ELISA •Inhibition Assays •Western Blotting |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa. |
Activity : | Not known. |
Storage : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. |
Gene Name : | CTSD cathepsin D [ Homo sapiens ] |
Synonyms : | CTSD; cathepsin D; CPSD; CLN10; MGC2311; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; EC 3.4.23.5; cathepsin D (lysosomal aspartyl protease);Cathepsin D light chain; Cathepsin D heavy chain |
Gene ID : | 1509 |
mRNA Refseq : | NM_001909 |
Protein Refseq : | NP_001900 |
MIM : | 116840 |
UniProt ID : | P07339 |
Chromosome Location : | 11p15.5 |
Pathway : | Lysosome |
Function : | aspartic-type endopeptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
CTSD-2752H | Recombinant Human CTSD Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctsd-2369M | Recombinant Mouse Ctsd Protein, His-tagged | +Inquiry |
CTSD-877H | Recombinant Human CTSD Protein, His-tagged | +Inquiry |
CTSD-2582H | Recombinant Human CTSD protein(71-410 aa), C-His-tagged | +Inquiry |
CTSD-435C | Recombinant Cricetulus Griseus CTSD Protein (65-408 aa), His-SUMO-tagged | +Inquiry |
◆ Native Protein | ||
CTSD-1648H | Active Native Human Cathepsin D | +Inquiry |
CTSD-189H | Active Native Human Cathepsin D | +Inquiry |
CTSD-26411TH | Active Native Human Cathepsin D protein | +Inquiry |
◆ Lysates | ||
CTSD-3023MCL | Recombinant Mouse CTSD cell lysate | +Inquiry |
CTSD-1735HCL | Recombinant Human CTSD cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0264 | Cathepsin D Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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