Recombinant Human CBL
Cat.No. : | CBL-26493TH |
Product Overview : | Recombinant fragment of Human CBL protein with an N terminal proprietary tag; predicted mwt: 36.63 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | NIQSQAPSITESSTFGEGNLAAAHA NTGPEESENEDDGYDVPKPPVPAVL ARRTLSDISNASSSFGWLSLDGDPT TNVTEGSQVPERPPKPFPRRINSER |
Sequence Similarities : | Contains 1 Cbl-PTB (Cbl-type phosphotyrosine-binding) domain.Contains 1 RING-type zinc finger.Contains 1 UBA domain. |
Gene Name : | CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence [ Homo sapiens ] |
Official Symbol : | CBL |
Synonyms : | CBL; Cas-Br-M (murine) ecotropic retroviral transforming sequence; CBL2; E3 ubiquitin-protein ligase CBL; c Cbl; oncogene CBL2; RNF55; |
Gene ID : | 867 |
mRNA Refseq : | NM_005188 |
Protein Refseq : | NP_005179 |
MIM : | 165360 |
Uniprot ID : | P22681 |
Chromosome Location : | 11q23.3-qter |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; CDC42 signaling events, organism-specific biosystem; Chronic myeloid leukemia, organism-specific biosystem; |
Function : | SH3 domain binding; calcium ion binding; ephrin receptor binding; ligase activity; phosphotyrosine binding; |
Products Types
◆ Recombinant Protein | ||
CBL-1801A | Recombinant Arabidopsis Thaliana CBL Protein (70-464 aa), His-SUMO-tagged | +Inquiry |
CBL-1263M | Recombinant Mouse CBL Protein, His (Fc)-Avi-tagged | +Inquiry |
CBL-2727H | Recombinant Human CBL Protein, MYC/DDK-tagged | +Inquiry |
CBL-513H | Recombinant Human CBL Protein, His (Fc)-Avi-tagged | +Inquiry |
Cbl-788M | Recombinant Mouse Cbl Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CBL-287HCL | Recombinant Human CBL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket