Recombinant Human CCBL2 Protein (1-454 aa), His-SUMO-tagged

• Cat.No.: CCBL2-1041H
• Product Overview: Recombinant Human CCBL2 Protein (1-454 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length.

Specification

• Description: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond . Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 67.4 kDa
• Protein length: 1-454 aa
• AA Sequence: MFLAQRSLCSLSGRAKFLKTISSSK ILGFSTSAKMSLKFTNAKRIEGLDS NVWIEFTKLAADPSVVNLGQGFPDI SPPTYVKEELSKIAAIDSLNQYTRG FGHPSLVKALSYLYEKLYQKQIDSN KEILVTVGAYGSLFNTIQALIDEGD EVILIVPFYDCYEPMVRMAGATPVF IPLRSKPVYGKRWSSSDWTLDPQEL ESKFNSKTKAIILNTPHNPLGKVYN REELQVIADLCIKYDTLCISDEVYE WLVYSGNKHLKIATFPGMWERTITI GSAGKTFSVTGWKLGWSIGPNHLIK HLQTVQQNTIYTCATPLQEALAQAF WIDIKRMDDPECYFNSLPKELEVKR DRMVRLLESVGLKPIVPDGGYFIIA DVSLLDPDLSDMKNNEPYDYKFVKW MTKHKKLSAIPVSAFCNSETKSQFE KFVRFCFIKKDSTLDAAEEIIKAWS VQKS
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: CCBL2 cysteine conjugate-beta lyase 2 [ Homo sapiens ]
• Official Symbol: CCBL2
• Synonyms: KAT3; KATIII; RP11-82K18.3; RP4-531M19.2
• Gene ID: 56267
• mRNA Refseq: NM_001008662.2
• Protein Refseq: NP_001008662.1
• MIM: 610656
• UniProt ID: Q6YP21