Recombinant Human CCT5 Protein, Myc/DDK-tagged

• Cat.No.: CCT5-001H
• Product Overview: Recombinant protein of human chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 59.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: CCT5 chaperonin containing TCP1 subunit 5 [ Homo sapiens (human) ]
• Official Symbol: CCT5
• Synonyms: CCT5; chaperonin containing TCP1 subunit 5; CCTE; HEL-S-69; PNAS-102; CCT-epsilon; TCP-1-epsilon; T-complex protein 1 subunit epsilon; chaperonin containing TCP1, subunit 5 (epsilon); epididymis secretory protein Li 69
• Gene ID: 22948
• mRNA Refseq: NM_012073
• Protein Refseq: NP_036205
• MIM: 610150
• UniProt ID: P48643