Recombinant Human CD14 Protein (Thr20-Leu368), His tagged
Cat.No. : | CD14-1291H |
Product Overview : | Recombinant human CD14 (Thr20-Leu368) fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL-. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 39.11 kDa |
Protein Length : | Thr20-Leu368 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | CD14 CD14 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD14 |
Synonyms : | CD14; CD14 molecule; CD14 antigen; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; |
Gene ID : | 929 |
mRNA Refseq : | NM_000591 |
Protein Refseq : | NP_000582 |
MIM : | 158120 |
UniProt ID : | P08571 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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