Recombinant Human CD180 Protein, C-His-tagged

• Cat.No.: CD180-096H
• Product Overview: Recombinant Human CD180 Protein with C-His tag was expressed in E. coli.

Specification

• Description: CD180/RP105 is a type-I transmembrane glycoprotein that is restricted to expression in mature B-cells. Research studies have shown that CD180 engages signaling cascades in mature B-cells that drive cell proliferation. Indeed, CD180 functions with TLR4 as an LPS receptor on B-cells and, upon binding LPS, transmits proliferation and survival signals that require the Vav family of guanine nucleotide exchange factors.
• Source: E. coli
• Species: Human
• Tag: C-His
• Molecular Mass: ~66 kDa
• AA Sequence: WDQMCIEKEANKTYNCENLGLSEIP DTLPNTTEFLEFSFNFLPTIHNRTF SRLMNLTFLDLTRCQINWIHEDTFQ SHHQLSTLVLTGNPLIFMAETSLNG PKSLKHLFLIQTGISNLEFIPVHNL ENLESLYLGSNHISSIKFPKDFPAR NLKVLDFQNNAIHYISREDMRSLEQ AINLSLNFNGNNVKGIELGAFDSTI FQSLNFGGTPNLSVIFNGLQNSTTQ SLWLGTFEDIDDEDISSAMLKGLCE MSVESLNLQEHRFSDISSTTFQCFT QLQELDLTATHLKGLPSGMKGLNLL KKLVLSVNHFDQLCQISAANFPSLT HLYIRGNVKKLHLGVGCLEKLGNLQ TLDLSHNDIEASDCCSLQLKNLSHL QTLNLSHNEPLGLQSQAFKECPQLE LLDLAFTRLHINAPQSPFQNLHFLQ VLNLTYCFLDTSNQHLLAGLPVLRH LNLKGNHFQDGTITKTNLLQTVGSL EVLILSSCGLLSIDQQAFHSLGKMS HVDLSHNSLTCDSIDSLSHLKGIYL NLAANSINIISPRLLPILSQQSTIN LSHNPLDCTCSNIHFLTWYKENLHK LEGSEETTCANPPSLRGVKLSDVKL SCG
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Concentration: ≥0.5 mg/mL
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: CD180 CD180 molecule [ Homo sapiens (human) ]
• Official Symbol: CD180
• Synonyms: CD180; CD180 molecule; CD180 antigen , LY64, lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD; CD180 antigen; Ly78; RP105; lymphocyte antigen 64; radioprotective 105 kDa protein; lymphocyte antigen-64, radioprotective, 105kDa; LY64; MGC126233; MGC126234
• Gene ID: 4064
• mRNA Refseq: NM_005582
• Protein Refseq: NP_005573
• MIM: 602226
• UniProt ID: Q99467