Recombinant Human CD27 Molecule, Fc-Tagged
Cat.No. : | CD27-56H |
Product Overview : | Recombinant Human CD27 Molecule, Fc-Tagged expressed in human cells is a disulfide-linked homodimeric protein. The reduced monomer comprises 420 amino acids and has a calculated molecular mass of 47.2 kDa. As a result of glycosylation, the monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CD27-56H |
Description : | Human CD27 is a lymphocyte-specific member of the TNF receptor superfamily. CD27 is expressed on a subset of human thymocytes and on the majority of mature T cells. CD27 expression is up-regulated after TCR stimulation. Within the CD4+ compartment, it is preferentially expressed on CD45RA+ cells. In contrast, it is preferentially expressed on CD45RO+ cells in the CD8+ compartment. CD27 also appeaars to be a potential marker for memory B cells. It exists as both a disulfide-linked dimer on the cell surface and as a soluble protein found in serum. Human CD27 is a 260 amino acid (aa) protein with a 20 aa signal, a 173 aa extracellular domain, a 20 aa transmembrane domain, and a 47 aa cytoplasmic domain. A DNA sequence encoding the extracellular domain (Met 1- Ile 192) of human CD27 (NP_001233.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the carboxy-terminus. |
Purity : | > 95%, as determined by SDS-PAGE and SEC-HPLC Analysis |
Predicted N terminal : | Thr 21 |
Formulation : | Supplied as a 0.2μm filtered solution of 100mM Glycine, 10mM NaCl,50 mM Tris, pH 7.5 |
Endotoxin : | < 1.0 EU per 1 μg of the cytokine as determined by the LAL method |
Reconstitution : | Follow the instructions on the vial. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Stability : | Samples are stable for up to twelve months from date of receipt -70C |
Storage : | Store at –70°C; Avoid repeated freeze-thaw cycles |
Gene Name : | CD27 |
Synonyms : | MGC20393; S152; T14; TNFRSF7; Tp55; CD27 antigen; CD27L receptor; CD27 molecule; T cell activation antigen CD27; T cell antivation antigen S152; tumor necrosis factor receptor superfamily, member 7; T-cell activation antigen CD27; CD27 |
Gene ID : | 939 |
mRNA Refseq : | NM_001242 |
Protein Refseq : | NP_001233 |
MIM : | 186711 |
UniProt ID : | P26842 |
Chromosome Location : | 12p13 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | caspase inhibitor activity; protein binding; transmembrane receptor activity. |
Products Types
◆ Recombinant Protein | ||
CD27-183H | Recombinant Human CD27 Protein, C-His-tagged | +Inquiry |
CD27-947R | Recombinant Rat CD27 Protein (Met1-Cys181), MlgG2a Fc-tagged | +Inquiry |
Cd27-2058M | Recombinant Mouse Cd27 Protein, Myc/DDK-tagged | +Inquiry |
CD27-622H | Recombinant Human CD27 Protein, Fc-tagged | +Inquiry |
CD27-1345H | Acitve Recombinant Human CD27 protein(Met1-Ile192), His-tagged | +Inquiry |
◆ Lysates | ||
CD27-1156CCL | Recombinant Cynomolgus CD27 cell lysate | +Inquiry |
CD27-2415MCL | Recombinant Mouse CD27 cell lysate | +Inquiry |
CD27-1383HCL | Recombinant Human CD27 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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