Recombinant Human CD27 Molecule, His-tagged
Cat.No. : | CD27-7139H |
Product Overview : | Recombinant human CD27 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 21.8 kDa. |
- Specification
- Gene Information
- Related Products
Description : | TNFRSF7, also known as CD27, is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Molecular Mass : | 21.8 kDa (196aa) |
Protein length : | 21-191aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMTPAPK SCPERHYWAQ GKLCCQMCEP GTFLVKDCDQ HRKAAQCDPC IPGVSFSPDH HTRPHCESCR HCNSGLLVRN CTITANAECA CRNGWQCRDK ECTECDPLPN PSLTARSSQA LSPHPQPTHL PYVSEMLEAR TAGHMQTLAD FRQLPARTLS THWPPQRSLC SSDFIR |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | CD27 CD27 molecule [ Homo sapiens ] |
Official Symbol : | CD27 |
Synonyms : | CD27; CD27 molecule; TNFRSF7, tumor necrosis factor receptor superfamily, member 7; CD27 antigen; S152; Tp55; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; T14; TNFRSF7; MGC20393; |
Gene ID : | 939 |
mRNA Refseq : | NM_001242 |
Protein Refseq : | NP_001233 |
MIM : | 186711 |
UniProt ID : | P26842 |
Chromosome Location : | 12p13 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding; receptor activity; transmembrane signaling receptor activity; |
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Cd27-2058M | Recombinant Mouse Cd27 Protein, Myc/DDK-tagged | +Inquiry |
Cd27-23R | Recombinant Rat Cd27 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD27-3228H | Active Recombinant Human CD27 protein(Met1-Ile192), rFc-tagged | +Inquiry |
Cd27-3273M | Active Recombinant Mouse Cd27 protein(Met1-Arg182), His-tagged | +Inquiry |
◆ Lysates | ||
CD27-1383HCL | Recombinant Human CD27 cell lysate | +Inquiry |
CD27-2415MCL | Recombinant Mouse CD27 cell lysate | +Inquiry |
CD27-1156CCL | Recombinant Cynomolgus CD27 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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