Recombinant Human CD276 Protein, His\Avi-tagged

• Cat.No.: CD276-174H
• Product Overview: Biotinylated Recombinant Human CD276/B7-H3 (C-Avi-His) is produced by Human Cells. The target gene encoding leu29-pro245 is expressed with a C-Avi-His tag.

Specification

• Description: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
• Source: Human Cells
• Species: Human
• Tag: His\Avi
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
• AA Sequence: leu29-pro245
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: CD276 CD276 molecule [ Homo sapiens (human) ]
• Official Symbol: CD276
• Synonyms: B7-H3; B7 homolog 3; B7H3; B7RP-2; 4Ig-B7-H3
• Gene ID: 80381
• mRNA Refseq: NM_001024736.2
• Protein Refseq: NP_001019907.1
• MIM: 605715
• UniProt ID: Q5ZPR3