Recombinant Human CD4 protein, His-tagged
Cat.No. : | CD4-1559H |
Product Overview : | Recombinant Human CD4 aa. (Lys26~Trp390) fused with N-terminal His tag was produced in E. coli cells. |
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Description : | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 44kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Lys26~Trp390 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method). |
Purity : | >95% |
Characteristic : | The isoelectric point is 9.2. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex. |
Gene Name : | CD4 CD4 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD4 |
Synonyms : | CD4mut; CD4 antigen (p55); CD4 receptor; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4 |
Gene ID : | 920 |
mRNA Refseq : | NM_000616.4 |
Protein Refseq : | NP_000607.1 |
UniProt ID : | P01730 |
Products Types
◆ Lysates | ||
CD4-2580MCL | Recombinant Mouse CD4 cell lysate | +Inquiry |
CD4-1905HCL | Recombinant Human CD4 cell lysate | +Inquiry |
CD4-947CCL | Recombinant Cynomolgus CD4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (3)
Ask a questionCD4 binds to glycoprotein GP120.
CD4 is mainly expressed in T cells and thymocytes.
CD4 is localized in the cell membrane.
Customer Reviews (3)
Write a reviewThe CD4 proteins purchased from your company is suitable for ELISA.
Protein products are put into experiments with good effect and reliable experimental results.
The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.
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