Recombinant Human CD40LG, His-tagged
Cat.No. : | CD40LG-27811TH |
Product Overview : | Recombinant full length soluble Human CD40LG with an N terminal His tag; 169 amino acids including tag, predicted MWt: 18.3kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. |
Protein length : | 149 amino acids |
Conjugation : | HIS |
Molecular Weight : | 18.300kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Specifically expressed on activated CD4+ T-lymphocytes. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 40% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMQKGD QNPQIAAHVISEASSKTTSVLQWAE KGYYTMSNNLVTLENGKQLTVKRQG LYYIYAQVTFCSNREASSQAPFIAS LCLKSPGRFERILLRAANTHSSAKP CGQQSIHLGGVFELQPGASVFVNVT DPSQVSHGTGFTSFGLLKL |
Sequence Similarities : | Belongs to the tumor necrosis factor family. |
Gene Name : | CD40LG CD40 ligand [ Homo sapiens ] |
Official Symbol : | CD40LG |
Synonyms : | CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; |
Gene ID : | 959 |
mRNA Refseq : | NM_000074 |
Protein Refseq : | NP_000065 |
MIM : | 300386 |
Uniprot ID : | P29965 |
Chromosome Location : | Xq26 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; |
Function : | CD40 receptor binding; cytokine activity; tumor necrosis factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
CD40LG-38H | Active Recombinant Human CD40LG Protein | +Inquiry |
CD40LG-634H | Recombinant Human CD40LG Protein | +Inquiry |
Cd40lg-4371M | Recombinant Mouse Cd40lg Protein | +Inquiry |
CD40LG-637M | Recombinant Mouse CD40LG Protein, Fc-tagged | +Inquiry |
CD40LG-0818H | Recombinant Human CD40LG Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CD40LG-1205RCL | Recombinant Rat CD40LG cell lysate | +Inquiry |
CD40LG-1080CCL | Recombinant Cynomolgus CD40LG cell lysate | +Inquiry |
CD40LG-1965HCL | Recombinant Human CD40LG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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