Recombinant Human CD46 Protein, His-tagged
Cat.No. : | CD46-151H |
Product Overview : | Recombinant Human CD46 molecule(CD46), transcript variant d(NM_153826), with a His tag, was expressed in human cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.146, without any preservatives. |
Molecular Mass : | 33.83kD |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | CD46 CD46 molecule, complement regulatory protein [ Homo sapiens ] |
Official Symbol : | CD46 |
Synonyms : | CD46; CD46 molecule, complement regulatory protein; antigen identified by monoclonal TRA 2 10 , CD46 antigen, complement regulatory protein , MCP, membrane cofactor protein (CD46, trophoblast lymphocyte cross reactive antigen) , MIC10; membrane cofactor protein; MGC26544; TLX; TRA2.10; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MCP; AHUS2; MIC10; |
Gene ID : | 4179 |
mRNA Refseq : | NM_002389 |
Protein Refseq : | NP_002380 |
MIM : | 120920 |
UniProt ID : | P15529 |
Products Types
◆ Recombinant Protein | ||
CD46-0822H | Recombinant Human CD46 Protein | +Inquiry |
CD46-0823H | Recombinant Human CD46 Protein, GST-Tagged | +Inquiry |
CD46-568R | Recombinant Rhesus Macaque CD46 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD46-394M | Recombinant Mouse CD46 Protein (45-329 aa), His-tagged | +Inquiry |
CD46-2331G | Recombinant Guinea Pig CD46 Protein (36-316 aa), His-tagged | +Inquiry |
◆ Lysates | ||
CD46-1964HCL | Recombinant Human CD46 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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