Recombinant Human CDC42BPA Protein (S2-Q473), GST tagged
Cat.No. : | CDC42BPA-1179H |
Product Overview : | Recombinant Human GST-TEV-GG-MRCKα(S2-Q473) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake. In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. Triggers the formation of an extrusion apical actin ring required for epithelial extrusion of apoptotic cells. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Protein Length : | S2-Q473 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) [ Homo sapiens (human) ] |
Official Symbol : | CDC42BPA |
Synonyms : | CDC42BPA; CDC42 binding protein kinase alpha (DMPK-like); CDC42 binding protein kinase alpha (DMPK like); serine/threonine-protein kinase MRCK alpha; FLJ23347; KIAA0451; MRCK; MRCKA; myotonic dystrophy kinase related Cdc42 binding kinase; PK428; MRCK alpha; DMPK-like alpha; ser-thr protein kinase PK428; CDC42 binidng protein kinase beta; myotonic dystrophy protein kinase-like alpha; CDC42-binding protein kinase alpha (DMPK-like); myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; ser-thr protein kinase related to the myotonic dystrophy protein kinase; DKFZp686L1738; DKFZp686P1738; |
Gene ID : | 8476 |
mRNA Refseq : | NM_003607 |
Protein Refseq : | NP_003598 |
MIM : | 603412 |
UniProt ID : | Q5VT25 |
Products Types
◆ Recombinant Protein | ||
CDC42BPA-0939H | Recombinant Human CDC42BPA Protein, GST-Tagged | +Inquiry |
CDC42BPA-0938H | Active Recombinant Human CDC42BPA Protein, GST-Tagged | +Inquiry |
CDC42BPA-936R | Recombinant Rat CDC42BPA Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42BPA-1178H | Recombinant Human CDC42BPA Protein (S2-Q473), Tag Free | +Inquiry |
CDC42BPA-26225TH | Recombinant Human CDC42BPA | +Inquiry |
◆ Lysates | ||
CDC42BPA-7654HCL | Recombinant Human CDC42BPA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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