Recombinant Human CDH1 Protein, His-tagged
Cat.No. : | CDH1-214H |
Product Overview : | Biotinylated (In vitro) Recombinant Human Cadherin-1 is produced by Human 293 Cells. The target gene encoding Q23-A709 is expressed with an 8His tag at the C terminus. |
- Specification
- Gene Information
- Related Products
Description : | E-Cadherin is a calcium-dependent cell adhesion glycoprotein that belongs to the cadherin family. E-Cadherin is expressed in non-neural epithelial tissues. It tends to interact with each other in a homophilic manner in connecting cells. E-Cadherin clusters are critical components of adherent junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier. E-Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. E-Cadherin loss contributes to cancer metastasis. The extracellular E-Cadherin N-terminal domain can be cleaved by several proteases and is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized frum a 0.2 um filtered solution of PBS, pH7.2. |
Molecular Mass : | Predicted Molecular Weight: 79.6kDa Apparent Molecular Weight: Biotinylated Cadherin-1 appeared between 66.2-116kDa in a reducing SDS-PAGE gel. |
AA Sequence : | Q23-A709 |
Endotoxin : | Less than 0.1 EU/ug. |
Purity : | >95% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. |
Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: greater than 95% as determined by reducing SDS-PAGE |
Shipping : | The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | CDH1 cadherin 1 [ Homo sapiens (human) ] |
Official Symbol : | CDH1 |
Synonyms : | Cadherin-1; CAM120/80; E-cadherin; CD324; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1 |
Gene ID : | 999 |
mRNA Refseq : | NM_001317184.2 |
Protein Refseq : | NP_001304113.1 |
MIM : | 192090 |
UniProt ID : | P12830 |
Products Types
◆ Recombinant Protein | ||
CDH1-208H | Recombinant Human CDH1 Protein, Fc-tagged | +Inquiry |
CDH1-946R | Recombinant Rat CDH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDH1-0969H | Recombinant Human CDH1 Protein, GST-Tagged | +Inquiry |
Cdh1-858M | Recombinant Mouse Cdh1 Protein, MYC/DDK-tagged | +Inquiry |
CDH1-41H | Recombinant Human CDH1 Protein, C-8His tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
CDH1-736RCL | Recombinant Rat CDH1 cell lysate | +Inquiry |
CDH1-1892MCL | Recombinant Mouse CDH1 cell lysate | +Inquiry |
CDH1-938HCL | Recombinant Human CDH1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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