Recombinant Human CDH3, His-tagged
Cat.No. : | CDH3-168H |
Product Overview : | Recombinant Human Cadherin-3/CDH3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu25-Gly654) of Human CDH3 fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
AA Sequence : | EPCRAVFREAEVTLEAGGAEQEPGQ ALGKVFMGCPGQEPALFSTDNDDFT VRNGETVQERRSLKE RNPLKIFPSKRILRRHKRDWVVAPI SVPENGKGPFPQRLNQLKSNKDRDT KIFYSITGPGADSPP EGVFAVEKETGWLLLNKPLDREEIA KYELFGHAVSENGASVEDPMNISII VTDQNDHKPKFTQDT FRGSVLEGVLPGTSVMQMTATDEDD AIYTYNGVVAYSIHSQEPKDPHDLM FTIHRSTGTISVISS GLDREKVPEYTLTIQATDMDGDGST TTAVAVVEILDANDNAPMFDPQKYE AHVPENAVGHEVQRL TVTDLDAPNSPAWRATYLIMGGDDG DHFTITTHPESNQGILTTRKGLDFE AKNQHTLYVEVTNEA PFVLKLPTSTATIVVHVEDVNEAPV FVPPSKVVEVQEGIPTGEPVCVYTA EDPDKENQKISYRIL RDPAGWLAMDPDSGQVTAVGTLDRE DEQFVRNNIYEVMVLAMDNGSPPTT GTGTLLLTLIDVNDH GPVPEPRQITICNQSPVRQVLNITD KDLSPHTSPFQAQLTDDSDIYWTAE VNEEGDTVVLSLKKF LKQDTYDVHLSLSDHGNKEQLTVIR ATVCDCHGHVETCPGPWKGGVDHHH HHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Gene Name : | CDH3 cadherin 3, type 1, P-cadherin (placental) [ Homo sapiens ] |
Official Symbol : | CDH3 |
Synonyms : | CDH3; cadherin 3, type 1, P-cadherin (placental); cadherin 3, P cadherin (placental); cadherin-3; CDHP; PCAD; calcium-dependent adhesion protein, placental; HJMD; |
Gene ID : | 1001 |
mRNA Refseq : | NM_001793 |
Protein Refseq : | NP_001784 |
MIM : | 114021 |
UniProt ID : | P22223 |
Chromosome Location : | 16q22.1 |
Pathway : | Adherens junctions interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; |
Function : | calcium ion binding; |
Products Types
◆ Recombinant Protein | ||
CDH3-1509M | Recombinant Mouse CDH3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cdh3-862M | Recombinant Mouse Cdh3 Protein, MYC/DDK-tagged | +Inquiry |
CDH3-4347H | Recombinant Human CDH3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDH3-2696H | Recombinant Human CDH3 protein(681-780 aa), C-His-tagged | +Inquiry |
CDH3-0989H | Recombinant Human CDH3 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CDH3-7636HCL | Recombinant Human CDH3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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