Recombinant Human CEACAM3 protein(Met1-Gly155), His-tagged

• Cat.No.: CEACAM3-3942H
• Product Overview: Recombinant Human CEACAM3 (NP_001806.2) (Met 1-Gly 155) was expressed in HEK293, with a polyhistidine tag at the C-terminus.

Specification

• Source: HEK293
• Species: Human
• Tag: C-His
• Protein length: Met1-Gly155
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human CEACAM3 consists of 132 amino acids and predictes a molecular mass of 14.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCEACAM3 is approximately 18-23 kDa due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 [ Homo sapiens ]
• Official Symbol: CEACAM3
• Synonyms: CEACAM3; carcinoembryonic antigen-related cell adhesion molecule 3; CGM1; CD66d; CD66d antigen; carcinoembryonic antigen CGM1; nonspecific cross-reacting antigen; carcinoembryonic antigen gene family member 1; CEA; W264; W282; CD66D; MGC119875
• Gene ID: 1084
• mRNA Refseq: NM_001815
• Protein Refseq: NP_001806
• MIM: 609142
• UniProt ID: P40198

Reviews

02/25/2022

Reliable data source, a dependable research ally.

12/22/2020

Top-notch analysis, vital for research outcomes.

11/18/2019

Expertise shines, an integral part of our research.

Q&As

How does CEACAM3 contribute to pathogen recognition?

It identifies pathogens by binding to their surfaces, aiding immune recognition.

What is the primary role of CEACAM3 in immune defense?

CEACAM3 is crucial for recognizing and responding to bacterial pathogens.

How does CEACAM3 interact with other immune receptors?

CEACAM3 works with immune receptors to coordinate bacterial defense.

How do genetic variations in CEACAM3 affect immune responses?

Genetic variations in CEACAM3 affect pathogen recognition and immune efficiency.

What is the impact of altered CEACAM3 activity on bacterial infections?

Altered CEACAM3 activity influences the body's ability to fight bacterial infections.

What role does CEACAM3 play in phagocytosis?

CEACAM3 is key in phagocytosis, helping to engulf and eliminate bacteria.

What potential therapeutic applications arise from targeting CEACAM3 in infectious diseases?

Targeting CEACAM3 could enhance immune responses against bacterial infections.