Recombinant Human CENPA, His-tagged
Cat.No. : | CENPA-27391TH |
Product Overview : | Recombinant Full Length Human CENPA produced in Sf9 Insect cells with a 6x His tag, 17,015 Dalton. |
- Specification
- Gene Information
- Related Products
Description : | Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Conjugation : | HIS |
Biological activity : | CENPA-27391TH reacts with Scleroderma patient sera. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 6M Urea, 20mM HEPES, 100mM Sodium chloride, pH 8 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the histone H3 family. |
Gene Name : | CENPA centromere protein A [ Homo sapiens ] |
Official Symbol : | CENPA |
Synonyms : | CENPA; centromere protein A; centromere protein A (17kD) , centromere protein A, 17kDa; histone H3-like centromeric protein A; CENP A; |
Gene ID : | 1058 |
mRNA Refseq : | NM_001042426 |
Protein Refseq : | NP_001035891 |
MIM : | 117139 |
Uniprot ID : | P49450 |
Chromosome Location : | 2p24-p21 |
Pathway : | Aurora A signaling, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; |
Function : | DNA binding; chromatin binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
CENPA-1359M | Recombinant Mouse CELA2A Protein (1-134 aa), His-tagged | +Inquiry |
CENPA-575H | Recombinant Human CENPA Protein, His (Fc)-Avi-tagged | +Inquiry |
CENPA-1575M | Recombinant Mouse CENPA Protein, His (Fc)-Avi-tagged | +Inquiry |
CENPA-1111H | Recombinant Human CENPA Protein, GST-Tagged | +Inquiry |
Cenpa-877M | Recombinant Mouse Cenpa Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CENPA-7587HCL | Recombinant Human CENPA 293 Cell Lysate | +Inquiry |
CENPA-7586HCL | Recombinant Human CENPA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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