Recombinant Human CENPH, His-tagged
Cat.No. : | CENPH-26924TH |
Product Overview : | Recombinant fragment corresponding to amino acids 136-247 of Human CENPH with an N terminal His tag; 133 amino acids with tag, Predicted MWt 15.5 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. |
Protein length : | 112 amino acids |
Conjugation : | HIS |
Molecular Weight : | 15.500kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMLNKL IMKSQQESWDLEEKLLDIRKKRLQL KQASESKLLEIQTEKNKQKIDLDSM ENSERIKIIRQNLQMEIKITTVIQH VFQNLILGSKVNWAEDPALKEIVLQ LEKNVDMM |
Sequence Similarities : | Belongs to the centromere protein H family. |
Gene Name : | CENPH centromere protein H [ Homo sapiens ] |
Official Symbol : | CENPH |
Synonyms : | CENPH; centromere protein H; NNF1; MIND kinetochore complex component; homolog (S. cerevisiae); PMF1; |
Gene ID : | 64946 |
mRNA Refseq : | NM_022909 |
Protein Refseq : | NP_075060 |
MIM : | 605607 |
Uniprot ID : | Q9H3R5 |
Chromosome Location : | 5p15.2 |
Pathway : | Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; M Phase, organism-specific biosystem; |
Function : | kinetochore binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
CENPH-1578M | Recombinant Mouse CENPH Protein, His (Fc)-Avi-tagged | +Inquiry |
Cenph-2104M | Recombinant Mouse Cenph Protein, Myc/DDK-tagged | +Inquiry |
CENPH-1116H | Recombinant Human CENPH Protein, GST-Tagged | +Inquiry |
CENPH-27395TH | Recombinant Human CENPH, His-tagged | +Inquiry |
CENPH-2687H | Recombinant Human CENPH protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CENPH-7584HCL | Recombinant Human CENPH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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