Recombinant Human CERS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CERS2-1277H
• Product Overview: LASS2 MS Standard C13 and N15-labeled recombinant protein (NP_071358) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 44.9 kDa
• AA Sequence: MLQTLYDYFWWERLWLPVNLTWADL EDRDGRVYAKASDLYITLPLALLFL IVRYFFELYVATPLAALLNIKEKTR LRAPPNATLEHFYLTSGKQPKQVEV ELLSRQSGLSGRQVERWFRRRRNQD RPSLLKKFREASWRFTFYLIAFIAG MAVIVDKPWFYDMKKVWEGYPIQST IPSQYWYYMIELSFYWSLLFSIASD VKRKDFKEQIIHHVATIILISFSWF ANYIRAGTLIMALHDSSDYLLESAK MFNYAGWKNTCNNIFIVFAIVFIIT RLVILPFWILHCTLVYPLELYPAFF GYYFFNSMMGVLQLLHIFWAYLILR MAHKFITGKLVEDERSDREETESSE GEEAAAGGGAKSRPLANGHPILNNN HRKNDTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CERS2 ceramide synthase 2 [ Homo sapiens (human) ]
• Official Symbol: CERS2
• Synonyms: CERS2; ceramide synthase 2; LAG1 homolog, ceramide synthase 2, LAG1 longevity assurance homolog 2 (S. cerevisiae), LASS2, longevity assurance (LAG1, S. cerevisiae) homolog 2; FLJ10243; SP260; LAG1 longevity assurance 2; LAG1 homolog, ceramide synthase 2; tumor metastasis-suppressor gene 1 protein; longevity assurance (LAG1, S. cerevisiae) homolog 2; L3; LASS2; TMSG1; MGC987
• Gene ID: 29956
• mRNA Refseq: NM_022075
• Protein Refseq: NP_071358
• MIM: 606920
• UniProt ID: Q96G23