Recombinant Human CFD Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CFD-3070H |
Product Overview : | CFD MS Standard C13 and N15-labeled recombinant protein (NP_001919) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 27 kDa |
AA Sequence : | MHSWERLAVLVLLGAAACAAPPRGR ILGGREAEAHARPYMASVQLNGAHL CGGVLVAEQWVLSAAHCLEDAADGK VQVLLGAHSLSQPEPSKRLYDVLRA VPHPDSQPDTIDHDLLLLQLSEKAT LGPAVRPLPWQRVDRDVAPGTLCDV AGWGIVNHAGRRPDSLQHVLLPVLD RATCNRRTHHDGAITERLMCAESNR RDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDS VLATRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CFD complement factor D [ Homo sapiens (human) ] |
Official Symbol : | CFD |
Synonyms : | CFD; complement factor D (adipsin); D component of complement (adipsin), DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN; |
Gene ID : | 1675 |
mRNA Refseq : | NM_001928 |
Protein Refseq : | NP_001919 |
MIM : | 134350 |
UniProt ID : | P00746 |
Products Types
◆ Recombinant Protein | ||
CFD-2178R | Recombinant Rat CFD Protein (26-263 aa), His-tagged | +Inquiry |
Cfd-546M | Recombinant Mouse Cfd Protein, MYC/DDK-tagged | +Inquiry |
CFD-790H | Recombinant Human CFD Protein | +Inquiry |
CFD-760H | Recombinant Human CFD Protein, His-tagged | +Inquiry |
CFD-2554H | Recombinant Human CFD Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
CFD-348H | Active Native Human Factor D | +Inquiry |
◆ Lysates | ||
CFD-1864HCL | Recombinant Human CFD cell lysate | +Inquiry |
CFD-1870MCL | Recombinant Mouse CFD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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