Recombinant Human CFTR-3C-eGFP Protein (M1-L1480 end), C-StrepII/10×His-tagged
Cat.No. : | CFTR-10H |
Product Overview : | Recombinant human CFTR(M1-L1480 end)-3C-eGFP-Strep II-10His was expressed in mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. |
Source : | Mammalian cell |
Species : | Human |
Tag : | C-StrepII/10×His |
Form : | Liquid |
Protein Length : | M1-L1480 end |
Endotoxin : | < 0.01 EU/μg of the protein |
Purity : | 80% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 20 mM Tris-HCl (pH 7.5), 2 mM MgCl2, 2 mM DTT, 200 mM NaCl, 0.06% digitonin |
Shipping : | It is shipped out with blue ice. |
Gene Name : | CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) [ Homo sapiens (human) ] |
Official Symbol : | CFTR |
Synonyms : | CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); ABCC7, CF, cystic fibrosis transmembrane conductance regulator, ATP binding cassette (sub family C, member 7); cystic fibrosis transmembrane conductance regulator; ABC35; ATP binding cassette sub family C; member 7; CFTR/MRP; dJ760C5.1; MRP7; TNR CFTR; cAMP-dependent chloride channel; channel conductance-controlling ATPase; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; CF; ABCC7; TNR-CFTR; |
Gene ID : | 1080 |
mRNA Refseq : | NM_000492 |
Protein Refseq : | NP_000483 |
MIM : | 602421 |
UniProt ID : | P13569 |
Products Types
◆ Recombinant Protein | ||
CFTR-1181H | Recombinant Human CFTR Protein, GST-Tagged | +Inquiry |
CFTR-1616M | Recombinant Mouse CFTR Protein, His (Fc)-Avi-tagged | +Inquiry |
CFTR-0456H | Recombinant Human CFTR Protein (M1-L1480 end), eGFP, Strep II, 10×His tagged | +Inquiry |
CFTR-2664H | Recombinant Human CFTR Protein, His (Fc)-Avi-tagged | +Inquiry |
CFTR-656R | Recombinant Rhesus Macaque CFTR Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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