Recombinant Human CHI3L1 Protein, His-tagged

• Cat.No.: CHI3L1-774H
• Product Overview: Recombinant Human CHI3L1 Protein (Asn112-Lys377) with His tag was expressed in E. coli.

Specification

• Description: Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.2 kDa; Accurate Molecular Mass: 26 kDa
• Protein length: Asn112-Lys377
• Purity: > 97%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) [ Homo sapiens (human) ]
• Official Symbol: CHI3L1
• Synonyms: CHI3L1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-3-like protein 1; GP39; YKL40; 39 kDa synovial protein; cartilage glycoprotein 39; ASRT7; GP-39; CGP-39; YKL-40; YYL-40; HC-gp39; HCGP-3P; hCGP-39; FLJ38139; DKFZp686N19119
• Gene ID: 1116
• mRNA Refseq: NM_001276
• Protein Refseq: NP_001267
• MIM: 601525
• UniProt ID: P36222