Recombinant Human CHRM3 Protein (253-492 aa), His-B2M-tagged

• Cat.No.: CHRM3-2276H
• Product Overview: Recombinant Human CHRM3 Protein (253-492 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Partial.

Specification

• Description: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
• Source: E. coli
• Species: Human
• Tag: His-B2M
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 40.7 kDa
• Protein length: 253-492 aa
• AA Sequence: RIYKETEKRTKELAGLQASGTEAET ENFVHPTGSSRSCSSYELQQQSMKR SNRRKYGRCHFWFTTKSWKPSSEQM DQDHSSSDSWNNNDAAASLENSASS DEEDIGSETRAIYSIVLKLPGHSTI LNSTKLPSSDNLQVPEEELGMVDLE RKADKLQAQKSVDDGGSFPKSFSKL PIQLESAVDTAKTSDVNSSVGKSTA TLPLSFKEATLAKRFALKTRSQITK RKRMSLVKEKKAAQT
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: CHRM3 cholinergic receptor, muscarinic 3 [ Homo sapiens ]
• Official Symbol: CHRM3
• Synonyms: CHRM3; acetylcholine receptor; muscarinic 3; m3 muscarinic receptor; HM3; EGBRS
• Gene ID: 1131
• mRNA Refseq: NM_000740
• Protein Refseq: NP_000731
• MIM: 118494
• UniProt ID: P20309