Recombinant Human CHRNA5 Protein, GST-Tagged

• Cat.No.: CHRNA5-1282H
• Product Overview: Human CHRNA5 partial ORF (NP_000736, 38 a.a. - 131 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.08 kDa
• AA Sequence: SEPSSIAKHEDSLLKDLFQDYERWV RPVEHLNDKIKIKFGLAISQLVDVD EKNQLMTTNVWLKQEWIDVKLRWNP DDYGGIKVIRVPSDSVWTP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) [ Homo sapiens ]
• Official Symbol: CHRNA5
• Synonyms: CHRNA5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; neuronal acetylcholine receptor subunit alpha-5; acetylcholine receptor; nicotinic; alpha 5 (neuronal); acetylcholine receptor, nicotinic, alpha 5 (neuronal); neuronal nicotinic acetylcholine receptor, alpha5 subunit; Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5; LNCR2
• Gene ID: 1138
• mRNA Refseq: NM_000745
• Protein Refseq: NP_000736
• MIM: 118505
• UniProt ID: P30532